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Illustrating the development of fair tests of treatments in health care
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INTERVENTIONS — BIOLOGICAL
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Nettleton T (1722)
Part of a letter from Dr. Nettleton, physician at Halifax, to Dr. Jurin, R. S. Sec concerning the inoculation of the small pox, and the mortality of that distemper in the natural way. Philosophical Transactions of the Royal Society of London (1722-1723) 32:209-212.
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Massey I (1723)
A short and plain account of inoculation. With some remarks on the main argument made use of to recommend that practice, by Mr. Maitland and others. To which is added, a letter to the learned James Jurin, M.D.R.S. Secr. Col. Reg. Med. Lond. Soc. London: W. Meadows.
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Jurin J (1724)
A letter to the learned Dr. Caleb Cotesworth, F. R. S. of the College of Physicians, London, and physician to St. Thomas's Hospital; containing a comparison between the danger of the natural small pox, and that given by inoculation. Philosophical Transactions of the Royal Society of London (1722 - 1723), 32:213-227.
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Boylston Z (1726)
Historical account of the small-pox inoculated in New-England, upon all sorts of persons, whites, blacks, and of all ages and constitutions. London: Printed for S. Chandler.
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Cassem Algaida Aga (1729)
Paper relating to the inoculation of the small-pox, as it is practised in the Kingdoms of Tripoli, Tunis, and Algier. In: Scheuchzer JG. An account of the success of inoculating the small-pox in Great Britain, for the years 1727 and 1728. London: J. Peele, pp 61-63.
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Scheuchzer JG (1729)
An account of the success of inoculating the small-pox in Great Britain, for the years 1727 and 1728: With a comparison between the mortality of the natural small-pox, and the miscarriages in that practice; as also some general remarks on its progress. London: J.Peele.
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de la Condamine C-M (1754)
Mémoire sur l'inoculation de la petite vérole. Lu a l'assemblée publique de l'Académie royale des sciences, le mercredi 24 avril 1754. Paris: Durand.
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Franklin B (1759)
Some account on the success of inoculation for the small-pox in England and America. London: W Strahan.
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Watson W (1768)
An account of a series of experiments, instituted with a view of ascertaining the most successful method of inoculating the smallpox. London: J Nourse.
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Gregory J (1772)
Lectures on the duties and qualifications of a physician. London: Strahan and Cadell. (new ed.) Edinburgh: Creech.
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Haygarth J (1784)
An inquiry into how to prevent smallpox. Chester and London.
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Black W (1789)
An arithmetical and medical analysis of the diseases and mortality of the human species. London: J Johnson.
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Haygarth J (1793)
Sketch of a plan to exterminate the casual smallpox from Great Britain; and to introduce general inoculation. London: J Johnson
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Sutton D (1796)
The Inoculator; or Suttonian system of inoculation, fully set forth in a plain and familiar manner. London: Printed for the author.
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Jenner E (1798)
An enquiry into the causes and effects of the variolae vaccinae. London: S Low.
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Jenner E (1801)
The origin of the vaccine inoculation. Printed by DN Shury, Berwick Street, Soho.
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Pearson G, Nihell L, Nelson T, Keate T, Forster T, Carpue JC, Doratt J, Rivers F, Brand EA, de Bruyn P, Heaviside J, Payne T, Sancho W (1805)
Original Vaccine Pock Institution. Edinburgh Medical and Surgical Journal 1:513-515.
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Bigelow J (1835)
A discourse on self-limited diseases, delivered before the Massachusetts Medical Society at their annual meeting, May 27, 1835. Boston: Nathan Hale p 8-10.
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Pasteur L (1881)
Compte rendu sommaire des expériences rates á Pouilly-le-Fort, prés Melun, sur la vaccination charbonneuse [A summary account of experiences at Pouilly-le-Fort, near Mélun, on anthrax vaccination]. Comptes rendus de l'Académie des Sciences 92: 1378-1383.
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Bettencourt R, Serrano J-A (1891)
Un cas de myxœdème (cachexie pachydermique) traité par la greffe hypodermique du corps thyroïde d’un mouton. [A case of myxœdema (pachydermous cachexia) treated with hypodermic transplant of sheep thyroid gland]. Compte rendu de la 19eme session de l‘Association française our l’avancement des sciences, Limoges, 1890, pp 683-690.
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Murray GR (1891)
Note on the treatment of myxoedema by hypodermic injections of an extract of the thyroid gland of a sheep. BMJ 2:796-797.
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Behring EA, Boer NN, Kossel H (1893)
Zur Behandlung diphtheriekranker Menschen mit Diphtherieheilserum [On the treatment of diphtheria patients with curative diphtheria serum]. Deutsche Medicinische Wochenschrift 17:389-39.
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Roux E, Martin L, Chaillou A (1894)
Trois cent cas de diphthérie traité par le serum antidiphthérique. Annales de l’Institut Pasteur 8:640-661.
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Brown EH (1896)
Cholera and its treatment by preventive inoculation in the Darbhanga Jail. Indian Medical Gazette, July, 247-250.
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Haffkine WM (1896)
Correspondence: Explanation of his inoculation report forms. Indian Medical Gazette 31:189-190.
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Pregl F (1896)
Zwei weitere ergographische Versuchsreihen über die Wirkung orchistischen Extraktes [Two further ergographic experimental series on the effects of testicular extracts]. Archiv für die gesamte Physiologie 62:379-399.
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Winters JE (1896)
Clinical observations upon the use of antitoxin in diphtheria: A report of personal investigation of this treatment in the principal fever hospitals of Europe during the summer of 1895. Medical Record 49:877-893.
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Heiberg P (1897)
Studier over den statistiske undersøgelsesmetode som hjælpemiddel ved terapeutiske undersøgelser [Studies on the statistical study design as an aid in therapeutic trials]. Bibliotek for Læger 89:1-40.
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Fibiger J (1898)
Om serumbehandling af difteri [On treatment of diphtheria with serum]. Hospitalstidende 6:309-325.
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Clemow (1899)
Yersin serum treatment of plague. BMJ 1:48.
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Cotton FJ (1899)
The Present Status of the Antistreptococcic Serum. New England Journal of Medicine 140:105-109. DOI: 10.1056/NEJM189902021400501
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Haffkine WM (1900)
On preventive inoculation. Proceedings of the Royal Society of London 65:252-271.
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Choksy NH (1900)
Professor Lustig’s plague serum. Lancet 2:291-292.
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Park WH (1900)
Use of diphtheria antitoxin in the treatment and prevention of diphtheria. JAMA 34: 902-904.
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Park WH (1900)
The quantity of diphtheria antitoxin required in the treatment of diphtheria. Archives of Paediatrics 17:823-827.
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Lustig A, Galeotti G (1901)
The prophylactic and curative treatment of plague. BMJ 1:206-208.
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Choksy NH (1901)
Plague treatment with Lustig’s serum. Indian Medical Gazette 36:154–155.
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Indian Plague Commission (1902)
Serum therapeutics. Investigations conducted by the commissioners. BMJ 1:1159-1160.
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Polverini G (1903)
Serumtherapie gegen Beulenpest Muenchener Medizinische Wochenschrift 50:649-651.
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Pearson K (1904)
Report on certain enteric fever inoculation statistics. BMJ 3:1243-1246.
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Bannerman WB (1905)
Introduction. In: Serum-therapy of plague in India. Scientific Memoirs by Officers of the Medical and Sanitary Departments of the Government of India. Calcutta, India: Office of the Superintendent of Government Printing, pp 1-27.
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Haffkine WM, West WG (1905)
Report on a series of 70 cases of plague treated with Brazil’s anti-plague serum. In: Bannerman WB, ed. Serum-therapy of plague in India. Scientific Memoirs by Officers of the Medical and Sanitary Departments of the Government of India. Calcutta, India: Office of the Superintendent of Government Printing, pp 47-59.
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Haffkine WM (1905)
Report on a series of 484 cases of plague treated with Lustig’s anti-plague serum. In: Bannerman WB, ed. Serum-therapy of plague in India. Scientific Memoirs by Officers of the Medical and Sanitary Departments of the Government of India. Calcutta, India: Office of the Superintendent of Government Printing, pp 27-36.
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Haffkine WM, Costello CT (1905)
Report on a series of 110 cases of plague treated with Terni’s anti-plague serum. In: Bannerman WB, ed. Serum-therapy of plague in India. Scientific Memoirs by Officers of the Medical and Sanitary Departments of the Government of India. Calcutta, India: Office of the Superintendent of Government Printing, pp 37-46.
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Rosenbach O (1905)
Die Diagnose als ätiologischer Factor [The diagnosis as a factor in aetiology]. Zeitschrift fur klinische Medicin 56:232-240.
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West WG (1905)
Report on a series of 68 cases of plague treated with Roux’ anti-plague serum. In: Bannerman WB, ed. Serum-therapy of plague in India. Scientific Memoirs by Officers of the Medical and Sanitary Departments of the Government of India. Calcutta, India: Office of the Superintendent of Government Printing, pp 60-7
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Choksy NH (1908)
On recent progress in serum-therapy of plague. BMJ 1:1282-1284.
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Freeman J (1910)
Vaccine therapy. Proceedings of the Royal Society of Medicine 3:97-101.
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Advisory Committee on Plague Investigations in India (1912)
The serum treatment of human plague. Journal of Hygiene. Plague Supplement II, LVI:326-39.
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Freeman RG (1912)
Serum treatment of pneumonia. JAMA 59:140.
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Park WH (1912)
The role of animal experimentation in the discoveries leading to our present knowledge of the etiology, prevention and cure of diphtheria. JAMA 53:453-459.
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Barnes HL (1912)
Report of 150 cases of pulmonary tuberculosis treated with tuberculin. JAMA 59:332-33.
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Rosenow EC, Hektoen L (1913)
Treatment of pneumonia with partially autolyzed pneumococci. JAMA 61:2203-4.
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Wright AE (1914)
On pharmaco-therapy and preventive inoculation applied to pneumonia in the African Native. London: Constable, p 84.
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Wright AE, Morgan WP, Colebrook L, Dodgson RW (1914)
Observations on prophylactic inoculation against pneumococcus infections, and on the results which have been achieved by it. Lancet 1:87-95
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Goadby K (1916)
An inquiry into the natural history of septic wounds. Lancet 188: 89-95.
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Leake JP (1917)
Bacterial vaccine therapy. JAMA 69:631-632.
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Von Sholly AI, Blum J, Smith L (1917)
The therapeutic value of pertussis vaccine in whooping cough. JAMA 68:1451-1456.
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Bingel A (1918)
Über Behandlung der Diphtherie mit gewöhnlichem Pferdeserum [On the treatment of diphtheria with normal horse serum]. Deutsches Archiv für Klinische Medizin 125:284-332.
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Kyes P (1918)
The treatment of lobar pneumonia with an anti-pneumococcus serum. Journal of Medical Research 38:495-501.
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McCoy GW, Murray VB, Teeter AL (1918)
The failure of a bacterial vaccine as a prophylactic against influenza. JAMA 71:1997.
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Lees D (1919)
Detoxicated vaccines in the treatment of gonorrhœa: the value of the complement-deviation test in controlling the treatment and estimating its therapeutic effect. Lancet 1:1107-1111.
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Leighton Kesteven H (1919)
A study of epidemic influenza in Australia. Lancet 2:1189-91.
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Mcguire LW, Redden WR (1919)
Treatment of Influenzal pneumonia by the use of convalescent human serum, Second report. JAMA 72:709-713. doi:10.1001/jama.1919.02610100017007
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Gray AW (1920)
Antipneumococcus serum (Kyes’s) in the treatment of pneumonia. American Journal of Medical Sciences 159:885-891.
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Banting FG, Best CH, Collip JB, Campell WR, Fletcher AA (1922)
Pancreatic extracts in the treatment of diabetes mellitus. Canadian Medical Association Journal 12: 141 - 146.
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Cecil RL, Larsen NP (1922)
Clinical and bacteriologic study of one thousand cases of lobar pneumonia. JAMA 79:343-349.
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Greenwood M (1924)
Is the statistical method of any value in medical research? Lancet 2: 153-158.
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Locke EA (1924)
The serologic treatment of lobar pneumonia. Boston Medical and Surgical Journal 190:196-203.
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Lewis S (1925)
Arrowsmith. New York: Collier.
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Malaria Commission of the Health Organisation (1925)
Report on its tour of investigation in certain European countries in 1924. Geneva: League of Nations. C.H. 273.
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Oliver WW, Stoller EA (1925)
Notes on the therapeutic value of pneumococcus antibody solution subcutaneously administered in lobar pneumonia. Archives of Internal Medicine 35:267-286.
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Park WH (1925)
Scarlet fever: etiology, prevention by immunization, and antitoxic treatment. JAMA 85:1180-1186.
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Swellengrebel NH (1925)
A summary of the more important facts on adult anophelines and their larvae observed by us or brought to our notice duing our tour through eastern Europe and Italy (May-September 1924). pp183-190. In: Malaria Commission of the Health Organisation (1925). Report on its tour of investigation in certain European countries in 1924. Geneva: League of Nations. C.H. 273.
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Wagner-Jauregg J (1926)
Die moderne Therapie der Neurolues [On modern therapy for neurosyphilis]. Verhandlungen der Deutschen Gesellschaft für Innere Medizin. Achtundreissigster Kongress. München: Bergmann, p 34-62.
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Ferguson FR, Davey AFC, Topley WWC (1927)
The value of mixed vaccines in the prevention of the common cold. Journal of Hygiene 26:98-109.
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Gordon E (1927)
Treatment of scarlet fever with streptococcus antitoxin. JAMA 88:382-5.
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Harries (1927)
Discussion on the serum treatment of scarlet fever. Proceedings of Royal Society of Medicine 20:1175–1176.
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Symmers D, Lewis KM (1927)
The antitoxin treatment of erysipelas: observations in one hundred and thirty-one patients at Bellevue Hospital. JAMA 89:880-2.
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Bullowa JGM (1928)
Use of antipneumococcic refined serum in lobar pneumonia: data necessary for a comparison between cases treated with serum and cases not so treated, and the importance of a significant control series of cases. JAMA 90: 1354-1358.
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Bullowa JGM (1928)
The control. Contribution to a symposium on the use of antipneumococcic refined serum in lobar pneumonia, 15 December 1927. Bulletin of the New York Academy of Sciences 4:339-343.
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Cecil RL, Sutliff WD (1928)
The treatment of lobar pneumonia with concentrated anti-pneumococcus serum. JAMA 91:2036-2040.
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Cecil RL (1928)
Specific treatment of lobar pneumonia. Archives of Internal Medicine 41:295-335.
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Ferry NS, Gordon EJ, Munro FW, Steele AH, Fisher LW (1928)
Clinical results with measles streptococcus toxin and antitoxin. JAMA 91:1277-1280.
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McCann WS (1928)
The serum treatment of erysipelas. JAMA 91:78-81.
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Park WH, Bullowa JGM, Rosenbluth NM (1928)
The treatment of lobar pneumonia with refined specific antibacterial serum. JAMA 91:1503-1508.
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Ross WC, Bagchi KN , Roy BC (1928)
The bacteriophage in cholera. Indian Journal of Medical Research 15:965-968.
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Bullowa JGM (1929)
The serum treatment and its evaluation in lobar pneumonia. Bulletin of the New York Academy of Medicine 5:328-362.
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Joe A, Swyer R (1929)
A study of passive immunisation in scarlet fever. Lancet 1:177-179.
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Benson WT (1930)
The treatment of erysipelas with vaccines. Lancet 2:1286-289.
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Cecil RL, Plummer N (1930)
Pneumococcus type I pneumonia - a study of eleven hundred and sixty-one cases, with especial reference to specific therapy. JAMA 95:1547-1553.
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Finland M (1930)
The serum treatment of lobar pneumonia. New England Journal of Medicine 202:1244-1247.
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Iversen P (1930)
Nogle bemærkninger om komplikationerne til parotitis epidemica og forsøg paa behandling med rekonvalescentserum [Treatment of complications of epidemic mumps with the serum of convalescents]. Ugeskrift for Læger 92:167-169.
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Kauders O (1930)
Ueber Nachbehandlung nach Malariatherapie [On the management of patients after malaria therapy]. Deutsche Medizinishe Wochenshcrift 61:400-401.
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Physicians to the Royal Infirmary, Edinburgh (1930)
A report on lobar pneumonia: treatment by concentrated antiserum. Lancet 2:1390-1394.
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Koenigsberger E (1931)
Die Behandlung der malignen Diphtherie, nach Erfahrungen in Berlin und Kopenhagen [Treatment of malignant diphtheria based on experiences in Berlin and Copenhagen]. Deutsche Medizinische Wochenschrift 57:842-845.
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Naidu BPB, Mackie FP (1931)
The serum therapy of plague. Lancet 2:893-897.
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Sutliff WD, Finland M (1931)
Type I lobar pneumonia treated with concentrated pneumococcic antibody (Felton). The clinical course. JAMA 96:1465-1469.
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Swyer R (1931)
Antigenic properties of diphtheria toxoid-antitoxin floccules. Lancet 1:632-634.
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Wagner-Jauregg J (1931)
Ueber die Infektionsbehandlung der progressiven Paralyse [On infection treatment of progressive paralysis]. Münchener Medizinische Wochenschrift 78:4-7.
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Aldred-Brown GRP, Munro JMH (1932)
Autogenous urinary proteose in rheumatoid arthritis. Lancet 2:1211-1214.
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Armstrong RR, Johnson RS (1932)
Treatment of lobar pneumonia by anti-pneumococcal serum. BMJ 2:662-65.
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Cecil RL, Plummer N (1932)
Pneumococcus Type II pneumonia: a clinical and bacteriologic study of one thousand cases, with especial reference to serum therapy. JAMA 98:779-86.
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Riding D, Corkhill NL (1932)
Prophylactic vaccination in epidemic meningococcal meningitis. Journal of Hygiene 32:258-267.
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Hottinger A, Toepfer D (1933)
Über den Wert der Serumtherapie bei Diphtherie, insbesondere bei der malignen, toxischen form [On the value of serum therapy of diphtheria, particularly in its malignant, toxic form]. Zeitschrifte für Kinderheilkunde 54:505-529.
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Kessel JF, Rose EJ (1933)
Bacteriophage Therapy in Bacillary Dysentery of the Flexner Type*†. Annals of Internal Medicine 6:1193-1199.
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Macnamara J (1933)
Serum therapy in poliomyelitis. BMJ 1:526-8.
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Sutliff WD, Finland M, Hunnicutt TN (1933)
Direct comparison between specific and nonspecific serum therapy for type 1 lobar pneumonia. Archives of Internal Medicine 51:435-446.
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Bullowa JGM (1934)
Therapeutic pneumococcus Type VIII (Cooper) serum. JAMA 102: 1560-1561.
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Medical Research Council Therapeutic Trials Committee (1934)
The serum treatment of lobar pneumonia. BMJ 1:241-245.
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Fischer A (1934)
Human Convalescent Serum in the Treatment of Preparalytic Poliomyelitis. Am J Dis Child 48: 481-501.
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McSweeny CJ (1935)
Clinical trials with a new antityphoid serum. Lancet 1:1095-1098.
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Begg N, Coveney MF (1936)
Whooping-cough: value of a specific vaccine in treatment. Lancet 1:82-83.
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Doull JA, Shibley GS, McClelland JE (1936)
Active immunization against whooping cough: interim report of the Cleveland experience. American Journal of Public Health 26:1097-1105.
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Gilliam AG, Onstott RH (1936)
Results of field studies with poliomyelitis vaccine. American Journal of Public Health 26:113-118.
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Hoyne AL (1936)
Intravenous treatment of meningococcic meningitis with Meningococcus antitoxin. JAMA 107:478-81.
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Pasricha CL, de Monte AJH, O’Flynn EG (1936)
Bacteriophage in the treatment of cholera. Indian Medical Gazette 71:61-68.
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Sutliff WD (1936)
Adequate tests of curative therapy in man. Annals of Internal Medicine 1936-1937;10:89-97.
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Bullowa JGM (1937)
Serum therapy. In: Bullowa JGM. The management of the pneumonias. New York: Oxford University Press, pp 283-298.
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Cookson H, Facey RV (1937)
Value of a specific serum in the treatment of typhoid fever. BMJ 1:1009-1012.
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Cunningham AA (1937)
Vaccine treatment of measles. BMJ 1:1202-1203.
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Pratt JP, Thomas WL (1937)
The endocrine treatment of menopausal phenomena. JAMA 109:1875-1880.
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Diehl HS, Baker AB, Cowan DW (1938)
Cold vaccines: an evaluation based on a controlled study. Journal of American Medical Association 111:1168-1173.
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Harrison WT, Franklin JP, Bell JA (1938)
Prophylactic value of a single dose of precipitated pertussis vaccine. Public Health Reports 53:793-796.
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Lash AF (1938)
Concentrated streptococcus (hemolytic) antitoxic serum in puerperal fever: further therapeutic studies. JAMA 110:1988-91.
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Nissen NI (1938)
Erfahrungen mit der Serumtherapie der kruppösen Pneumonie. [Experiences with serum therapy of pneumonia with croup]. Deutsche Medizinische Wochenschrift 64:221-225.
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Orenstein AJ (1938)
Report for the year 1937. Health Department, Central Mining-Rand Mines Group, p 8.
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Peters BA (1938)
A comparative test of natural and concentrated anti-toxin in treatment of malignant diphtheria. BMJ 2:344-346.
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Kendrick P, Eldering G (1939)
A study in active immunization against pertussis. American Journal of Hygiene 29 Sec. B:133-153.
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Murless BC (1939)
Effect of follicular hormone on menopausal flushes. Lancet 233:1205-1206.
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Pasricha CL, de Monte AJH, Chatterjee BC, Mian AS (1939)
Treatment of cholera (A note on the results of treatment by different methods). Indian Medical Gazette 74:400-401.
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Top FH, Young DC (1939)
Specific and non-specific serum treatment of scarlet fever. American Journal of Public Health 29:443-451.
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Volini IF, Levitt RO (1939)
The treatment of Pneumococcic pneumonia with concentrated rabbit serum. JAMA 113: 1314-6.
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Gregory KK, West EJ, Stevens RE (1940)
Epidemic cerebrospinal meningitis (meningococcic): the treatment of 113 patients with antimeningococcus serum, meningococcus antitoxin and sulfanilamide. JAMA 115:1091-5.
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Sidell N, Abrams MI (1940)
Treatment of chronic arthritis. JAMA 144:1740-1742.
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Bell JA (1941)
Pertussis prophylaxis with two doses of alum-precipitated vaccine. Public Health Reports 56:1535-1546.
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Ewalt JR, Ebaugh FG (1941)
Treatment of dementia paralytica: A five year comparative study of artificial fever therapy and therapeutic malaria in two hundred and thirty-two cases. JAMA 116:2474-77.
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Fleming JB (1941)
Treatment of diphtheria. BMJ 1:907.
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Kaufman P (1941)
Studies on old age pneumonia. II. Prophylactic effect of pneumococcus polysaccharide against pneumonia. Archives of Internal Medicine 61:304-319.
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Libertson W (1941)
A critical analysis of insulin therapy at Rochester State Hospital. Psychiatric Quarterly 15: 635-647.
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Top FH, Young DC (1941)
The treatment of moderately severe scarlet fever: A study of alternate patients treated with sulfanilamide, convalescent serum and scarlet fever antitoxin. JAMA 117:2056-60.
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Kendrick PL (1942)
Use of alum-treated pertussis vaccine, and alum-precipitated combined pertussis vaccine and diphtheria toxoid, for active immunization. American Journal of Public Health 32:615-626.
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Kendrick PL (1943)
Field study of alum-precipitated combined pertussis vaccine and diphtheria toxoid for active immunization. American Journal of Hygiene 38:193-202.
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Sigler LH, Tulgan J (1943)
Treatment of angina pectoris by testosterone propionate. New York State Journal of Medicine 43:1424-1428.
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Boyd JSK, Portnoy B (1944)
Bacteriophage therapy in bacillary dysentery. Transactions of the Royal Society of Tropical Medicine and Hygiene 37:243-262.
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Commission on Influenza (1944)
A clinical evaluation of vaccination against influenza. JAMA 124:982-985.
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Wolman M (1944)
Treatment of typhus with anti-typhus horse serum. Lancet 2:210-12.
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Wright J, Cruickshank R, Gunn W (1944)
The control of dust-borne streptococcal infection in measles wards. BMJ 1:611-614.
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Bransby ER, Hunter JW, Magee HE, Milligan EHM, Rodgers TS (1944)
The influence of supplements of vitamins A, B
1
, B
2
, C, and D on growth, health and physical fitness. BMJ 1:77.
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MacLeod CM, Hodges RG, Heidelberger M, Bernhard WG (1945)
Prevention of pneumococcal pneumonia by immunization with specific capsular polysaccharides. Journal of Experimental Medicine 82:445-465.
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Bahlke AM, Perkins JE (1945)
Gamma globulin in poliomyelitis. JAMA 129:1146-1150.
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Gellis SS, Stokes J, Forster HW, Brother GM, Hall WM (1945)
The use of human immune serum globulin (gamma globulin) in infectious (epidemic) hepatitis in the Mediterranean theater of operations II. Studies on treatment in an epidemic of infectious hepatitis. JAMA 128:1158-9.
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Grossman EB, Stewart SG, Stokes J (1945)
Post-transfusion hepatitis in battle casualties: and a study of its prophylaxis by means of human immune serum globulin. JAMA 129:991-4.
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Havens WP, Paul JR (1945)
Prevention of infectious hepatitis with gamma globulin. JAMA 129:270-272.
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McFarlan AM, Topley E, Fisher M (1945)
Trial of whooping-cough vaccine in city and residential nursery groups. BMJ 2:205-208.
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Rosenthal SR, Blahd M, Leslie EI (1945)
Ten years’ experience with BCG (experimental and clinical). Journal of Pediatrics 26:470-80.
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Aronson JD, Palmer CE (1946)
Experience with BCG vaccine in the control of tuberculosis among North American Indians. Public Health Reports 61:802-820.
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Levine MI, Sackett MF (1946)
Results of BCG vaccination in New York City. American Review of Tuberculosis 53:517-532.
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Hirsh HL, Rotman-Kavka, G, Dowling HF, Sweet LK (1947)
Penicillin therapy of scarlet fever: comparison with antitoxin and symptomatic therapy. JAMA 133:657-61.
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Robinson M (1947)
Hormonal treatment of deficient lactation. Lancet 2:90-92.
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Bell JA (1948)
The epidemiological principles and procedures involved in a study of the prophylactic value of an alum-precipated mixture of diphtheria toxoid and pertussis vaccine. Thesis submitted to the School of Hygiene and Public Health of the Johns Hopkins University in conformity with the requirements for the Degree of Doctor of Public Health.
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Bell JA (1948)
Diphtheria immunization use of an alum-precipitated mixture of pertussis vaccine and diphtheria toxoid. JAMA 137:1009-1016.
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Bell JA (1948)
Pertussis immunization use of two doses of an alum-precipitated mixture of diphtheria toxoid and pertussis vaccine. JAMA 137:1276-1281.
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Mellanby H, Andrewes CH, Dudgeon JA, Mackay DG (1948)
Vaccination against influenza A. Lancet 251:978-982.
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Bingel A (1949)
Wirkt das Diphtherieheilserum bei der menschlichen Diphtheriekrankheit spezifisch durch seinen Antitoxingehalt oder unspezifisch [Does curative diphtheria serum act specifically through its anti-toxin content or non-specifically in human diphtheria]? Deutsche Medizische Wochenschrift 74:101-103.
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Ferguson RG, Simes AB (1949)
BCG vaccination of Indian infants in Saskatchewan. Tubercle 30:5-11 30:5-11.
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Kaufman P (1949)
Pneumonia in old age: active immunization against pneumonia with pneumococcus polysaccharide results of a six your study. Archives of Internal Medicine 79:518-531.
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Appleby JC, Himmelweit F, Stuart-Harris CH (1951)
Immunization with influenza virus A vaccines. Comparision of intradermal and subcutaneous routes. Lancet 1:1384-1387.
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Medical Research Council (1951)
The prevention of whooping-cough by vaccination. BMJ 1:1463-1471.
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Hammon W, Coriell LL, Stokes J (1952)
Evaluation of red cross gamma globulin as a prophylactic agent for poliomyelitis: 1. Plan of controlled field tests and results of 1951 pilot study in Utah. JAMA 150:739-749.
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Rheumatic Fever Working Party of the Medical Research Council of GB and the subcommittee of principal investigators of the American Council on Rheumatic Fever and Congenital Heart Disease, American Heart Association. (1955)
Treatment of acute rheumatic fever in children; a co-operative clinical trial of A.C.T.H., Cortisone, and Aspirin. BMJ 1:555-574
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Bjerkelund CJ (1957)
The effect of long-term treatment with dicoumarol in myocardial infarction. A controlled clinical study. Acta Med Scand Suppl 330:1-212.
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Gam F, Helles A, Andersen B (1977)
Hormonal treatment of climacteric complaints. A controlled, double-blind comparative study between 2 different types of sequential estrogen-gestagen preparations [in Danish]. Ugeskr Laeger 139:2808-12.
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Foon KA, Smalley RV, Riggs CW, Gale RP (1983)
The role of immunotherapy in acute myelogenous leukemia. Arch Intern Med 143: 1726-1731
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Yokley JM, Glenwick DS (1984)
Increasing the immunization of preschool children; An evaluation of applied community interventions. Journal of Applied Behavior Analysis 17:313-325.
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Roifman CM, Levison H, Gelfand EW (1987)
High-dose versus low-dose intravenous immunoglobulin in hypogammaglobulinaemia and chronic lung disease. Lancet 329: 1075–1077.
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Chalmers I, ed (1988)
The Oxford Database of Perinatal Trials. Oxford: Oxford University Press.
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Chalmers I, Enkin M, Keirse MJNC (1989)
Effective care in pregnancy and childbirth. Oxford: Oxford University Press.
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Gray R, Wheatley K (1991)
How to avoid bias when comparing bone marrow transplantation with chemotherapy. Proceedings of the International Course on Bone Marrow Transplantation in Children, 28 Nov-1 Dec 1990, Erice, Italy. Bone Marrow Transplantation 7, Suppl 3:9-12.
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Sinclair JC, Bracken MB (1992)
Effective care of the newborn infant. Oxford: Oxford University Press.
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Cochrane Pregnancy and Childbirth Group (1994)
The Cochrane Pregnancy and Childbirth Database. Oxford: Update Software
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Stockwell MS, CaCamargo S, Ramakrishnan R, Holleran S, Findley SE, Kukafka R, Hofstetter AM, Fernandez N, Vawdrey DK (2015)
Registry-linked electronic influenza vaccine provider reminders: a cluster-crossover trial. Pediatrics. 135:e75-82.
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Cohen D (2018)
Oxford TB vaccine study calls into question selective use of animal data. BMJ 360:j5845 doi: 10.1136/bmj.j5845
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Show
ALL ARTICLES
Brief histories
Commentaries
Biographies
Personal reflections
Doctoral theses
Hróbjartsson A, Gøtzsche PC, Gluud C (1988).
The controlled clinical trial turns 100 years: Fibiger’s trial of serum treatment of diphtheria. JLL Bulletin: Commentaries on the history of treatment evaluation.
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Tröhler U (2003).
Adolf Bingel (1879-1953), a member of the last generation of general internal physicians in Germany. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Armitage P† (2003).
Some recollections of the early years of the Medical Research Council (MRC) Statistical Research Unit. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Huth EJ (2005).
Quantitative evidence for judgments on the efficacy of inoculation for the prevention of smallpox: England and New England in the 1700s. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Huth EJ (2006).
Benjamin Franklin’s (1706-1790), place in the history of medicine. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Jefferson T (2006).
Why the MRC randomized trials of whooping cough (pertussis) vaccines remain important more than half a century after they were done. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Marks HM† (2006).
The Kendrick-Eldering-(Frost) pertussis vaccine field trial. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Neuhauser D, Diaz M (2006).
Jesse GM Bullowa (1879-1943). JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Boylston AW (2008).
Zabdiel Boylston (1679/80-1766). JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Boylston AW (2008).
William Watson’s use of controlled clinical experiments in 1768. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Boylston AW, Williams AE (2008).
Zabdiel Boylston’s evaluation of inoculation against smallpox. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Podolsky SH (2008).
Jesse Bullowa, specific treatment for pneumonia, and the development of the controlled clinical trial. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Shannon H (2008).
A statistical note on Karl Pearson’s 1904 meta-analysis. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Stylianou C, Kelnar C (2008).
The introduction of successful treatment of diabetes mellitus with insulin. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Boylston AW (2010).
Thomas Nettleton and the dawn of quantitative assessments of the effects of medical interventions. JLL Bulletin: Commentaries on the history of treatment evaluation.
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Chalmers I (2010).
Joseph Asbury Bell (1904-1968). JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Chalmers I (2010).
Joseph Asbury Bell and the birth of randomized trials. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Gluud C (2010).
Danish contributions to the evaluation of serum therapy for diphtheria in the 1890s. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Klingberg MA (2010).
An epidemiologist’s journey from typhus to thalidomide, and from the Soviet Union to Seveso. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Löwy I (2010).
Martin Arrowsmith’s clinical trial: scientific precision and heroic medicine. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Morabia A (2010).
Edward Jenner’s 1798 report of challenge experiments demonstrating the protective effects of cowpox against smallpox. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Opinel A, Gachelin G (2010).
French 19th century contributions to the development of treatments for diphtheria. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Slater SD (2010).
The discovery of thyroid replacement therapy. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Tröhler U (2010).
Towards endocrinology: Theodor Kocher’s 1883 account of the unexpected effects of total ablation of the thyroid. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Tröhler U (2010).
Adolf Bingel’s blinded, controlled comparison of different anti-diphtheritic sera in 1918. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Tröhler U (2010).
Emil Theodor Kocher (1841-1917). JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Boylston AW (2011).
Observation and experimentation in developing ‘the Suttonian Method’ of inoculation. JLL Bulletin: Commentaries on the history of treatment evaluation.
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Chalmers I, Dukan E, Podolsky SH, Davey Smith G (2011).
The advent of fair treatment allocation schedules in clinical trials during the 19th and early 20th centuries. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Fox DM (2011).
Systematic reviews and health policy: the influence of a project on perinatal care since 1988. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Gartlehner G, Stepper K (2011).
Julius Wagner-Jauregg: pyrotherapy, Simultanmethode, and ‘racial hygiene’. JLL Bulletin: Commentaries on the history of treatment evaluation.
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Podolsky SH, Davey Smith G (2011).
Park’s story and Winters’ tale: alternate allocation clinical trials in turn of the Century America. JLL Bulletin: Commentaries on the history of treatment evaluation.
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Boylston AW (2012).
The origins of vaccination: no inoculation, no vaccination. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Boylston AW (2012).
John Haygarth’s 18th century ‘Rules of Prevention’ for eradicating smallpox. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Boylston AW (2012).
The origins of inoculation. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Ramanna M (2014).
Nasarwanji Hormusji Choksy (1861-1939), a pioneer of controlled clinical trials. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Bird A (2018).
James Jurin and the avoidance of bias in collecting and assessing evidence on the effects of variolation. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Jefferson T (2019).
Sponsorship bias in clinical trials – growing menace or dawning realisation? JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Tröhler U (2020)
Probabilistic thinking and the evaluation of therapies, 1700-1900. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Gøtzsche PC (2021).
Citation bias: questionable research practice or scientific misconduct? JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Ritskes-Hoitinga M, Pound P (2022).
The role of systematic reviews in identifying the limitations of preclinical animal research, 2000 – 2022. JLL Bulletin: Commentaries on the history of treatment evaluation.
View
Chalmers I, Matthews R, Glasziou P, Boutron I, Armitage P† (2023).
Analysis of clinical trial by Treatment Allocated or by Treatment Received? Applying ‘the intention-to-treat principle’. JLL Bulletin: Commentaries on the history of treatment evaluation.
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Nylenna, M (2023).
Paul Owren, Christopher Bjerkelund and the dawn of controlled trials in Norway. JLL Bulletin: Commentaries on the history of treatment evaluation.
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Glasziou P, Matthews R, Boutron I, Chalmers I, Armitage P† (2023)
The differences and overlaps between ‘explanatory’ and ‘pragmatic’ controlled trials: a historical perspective. JLL Bulletin: Commentaries on the history of treatment evaluation.
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