Park WH (1900)

Use of diphtheria antitoxin in the treatment and prevention of diphtheria. JAMA 34: 902-904.
In 1900, the American physician William Park described his use of alternation  to create comparison groups in a test of the effects of anti-diphtheritic serum in children.

Key passage(s)

Park_1900a_kp

Whole article

Acknowledgements

The editors are grateful to:

JAMA for allowing the James Lind Library to link to this and other articles of historical relevance (email to Iain Chalmers from Annette Flanagin, 29 August 2014).