Newcombe RG (1988) - The James Lind Library The James Lind Library

Newcombe RG (1988)

Explanatory and pragmatic estimates of the treatment effect when deviations from allocated treatment occur. . Statistics in Medicine Volume 7, Issue 11 p. 1179-1186.
When deviations from randomly allocated treatment occur, an attenuation factor can be used to obtain and estimate of the underlying difference in effectiveness between the two treatments, corresponding to an explanatory paradigm.

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Newcombe RG (1988). Explanatory and pragmatic estimates of the treatment effect when deviations from allocated treatment occur. Statistics in Medicine Volume 7, Issue 11 p. 1179-1186.

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