Double dummy

In a double dummy trial, there are usually two placebos.


JLL Essay
The need to avoid differences in the way outcomes are assessed

Fair tests of treatments

 

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Dudley Hart F, Boardman PL (1965)
Indomethacin and phenylbutazone: a comparison. BMJ 2:1281-1284.

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Wright V, Walker WC, McGuire RJ (1969)
Indomethacin in the treatment of rheumatoid arthritis. Annals of Rheumatic Diseases 28:157-162.

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Assaf RA, Dundee JW, Gamble JA (1975)
The influence of the route of administration on the clinical action of diazepam. Anesthesia 30:152-8.

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Dürrigl T, Vitaus, Pucar I, Miko M (1975)
Diclofenac sodium (Voltaren): results of a multicentre comparative trial in adult-onset rheumatoid arthritis. Journal of International Medical Research 3:139-44.

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Harding SM, Heath S (1976)
Intranasal steroid aerosol in perennial rhinitis: comparison with an antihistamine compound. Journal of Clinical Allergy 6:369-72.

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Wettrell K (1977)
Intraocular pressure reduction during treatment with pilocarpine and systemic propranolol. A comparative double-masked study. Albrecht Von Graefes Arch Klin Exp Ophthalmol 204:1-7.

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Murphy JE (1977)
A comparative trial of Anafranil, Pertofran and an Anafranil/Pertofran combination. Journal of International Medical Research 5(1 Suppl):16-23.

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Gam F, Helles A, Andersen B (1977)
Hormonal treatment of climacteric complaints. A controlled, double-blind comparative study between 2 different types of sequential estrogen-gestagen preparations [in Danish]. Ugeskr Laeger 139:2808-12.

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Beaver WT, Feise GA (1977)
A comparison of the analgesic effect of oxymorphone by rectal suppository and intramuscular injection in patients with postoperative pain. Journal of Clinical Pharmacology 17:276-91.

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Donald JF, Molla AL (1978)
A controlled study comparing a three times daily dose of chlordiazepoxide with a single night-time dose of Trancopal in the control of anxiety, using a double-blind, double-dummy technique. J Int Med Res 6:105-10.

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Rhind VM, Leatham PA, Wright V, Akbar FA, Downie WW (1978)
A comparative study of floctafenine (Idarac) and ibuprofen in the treatment of osteoarthrosis. Journal of International Medicial Research 2:11-13.

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Mirakhur RK, Dundee JW, Connolly JD (1979)
Studies of drugs given before anaesthesia. XVII: anticholinergic premedicants. British Journal of Anesthesia 51:339-45.

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Blohmé G, Waldenström J (1979)
Glibenclamide and glipizide in maturity onset diabetes. A double-blind cross-over study. Acta Medica Scandinavica 206:263-7.

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