Schoeler T, Speed D, Porcu E, Pirastu N, Pingault JB, Kutalik Z (2023)
Participation bias in the UK Biobank distorts genetic associations and downstream analyses. Nat Hum Behav. 2023 Jul;7(7):1216-1227. doi: 10.1038/s41562-023-01579-9.
Example of how non-random nature of recruitment to a "big data" project leads to bias that can undermine estimates of the magnitude of genetic influence on health.