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James Lind LibraryThe James Lind Library
Illustrating the development of fair tests of treatments in health care

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Anderson T (1944)

Clinical studies in sulphonamide chemotherapy. MD thesis, University of Glasgow.

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Anderson T (1944). Clinical studies in sulphonamide chemotherapy. MD thesis, University of Glasgow.

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Thomas Goodwillie Anderson

Thomas Goodwillie Anderson, while Henry Mechan Chair of Public Health, University of Glasgow, with thanks to Public Health, Institute of Health and Wellbeing, University of Glasgow.

RELEVANT TOPICS

  • Fair tests of treatments
  • Biases
  • Allocation bias
  • Observer bias
  • Quantifying uncertainty

Key articles

  • Toth B (2018).
    Pioneering controlled trials of treatments for erysipelas and pneumonia in Glasgow, 1936-47.

All topics

  • Fair tests of treatments
    • The need to address treatment uncertainties
      • Principles of Testing
    • Treatment comparisons are essential
      • Placebo effects
      • Dramatic effects
    • Treatment comparisons must be fair
  • Biases
    • Design bias
    • Allocation bias
      • N-of-1 crossover
      • Cluster allocation
      • Factorial design
      • Crossover tests
    • Co-intervention bias
    • Observer bias
      • Double dummy
    • Analysis bias
    • Biases in judging unanticipated possible effects
    • Reporting bias
    • Biases in systematic reviews
    • Researcher/sponsor bias and fraud
  • The play of chance
    • Recording and interpreting numbers
    • Quantifying uncertainty
    • Using meta-analysis
  • Bringing it all together for the benefit of patients and the public
    • Improving reports of research
    • Preparing and maintaining systematic reviews
    • Using the results of research

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