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Doing clinical trials large enough to achieve adequate reductions in uncertainties about treatment effects.
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Thomas C Chalmers (1917-1995): a pioneer of randomized clinical trials and systematic reviews.
- Clarke M (2015).
History of evidence synthesis to assess treatment effects: personal reflections on something that is very much alive.
- Fair tests of treatments
- The play of chance
- Bringing it all together for the benefit of patients and the public