Chalmers TC (1968)

When should randomisation begin? Lancet 1:858.
From the 1960s until his death in the 1990s, the American physician Thomas Chalmers was one of the most vocal promoters of clinical trials, suggesting that inadequately evaluated new treatments should only be used in randomized trials until their effects became known.

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 Thomas. C. Chalmers (1917-1995)



The editors are grateful to:

Elsevier Ltd. for making a pdf of this article available  (letter to Iain Chalmers from Laura Pritchard, 14 May 2014). For conditions of further reproduction, see here.

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