Antman EM, Lau J, Kupelnick B, Mosteller F, Chalmers TC (1992)

A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. JAMA 268:240-248.
The 1992 comparison of textbook recommendations with the results of clinical trials reported by Elliott Antman, Joseph Lau, Bruce Kupelnick, Frederick Mosteller and Thomas Chalmers showed that patients had died avoidably because textbooks had not reviewed reliable research evidence systematically.

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Whole article

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Antman EM, Lau J, Kupelnick B, Mosteller F, Chalmers TC (1992). JAMA 268(2):240-48.

Portrait(s)

Thomas. C. Chalmers (1917-1995)

chalmers_portrait

Other material(s)

Altman 1992 Timeline image

Acknowledgements

The editors are grateful to:

JAMA for allowing the James Lind Library to link to this and other articles of historical relevance (email to Iain Chalmers from Annette Flanagin, 29 August 2014).

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