Amberson JB, McMahon BT, Pinner M (1931)

A clinical trial of sanocrysin in pulmonary tuberculosis. American Review of Tuberculosis 24:401-435.
To test the effects of a gold salt (Sanocrysin for pulmonary tuberculosis, Amberson and his colleagues decided using a coin toss which group of patients would receive the drug and which would be retained for comparison.

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James Burns Amberson Jr (1890-1979)amberson_port