Amberson JB, McMahon BT, Pinner M (1931) - The James Lind Library The James Lind Library

Amberson JB, McMahon BT, Pinner M (1931)

A clinical trial of sanocrysin in pulmonary tuberculosis. American Review of Tuberculosis 24:401-435.
To test the effects of a gold salt (Sanocrysin for pulmonary tuberculosis, Amberson and his colleagues decided using a coin toss which group of patients would receive the drug and which would be retained for comparison.

Key passage(s)

Portrait(s)

James Burns Amberson Jr (1890-1979)

RELEVANT TOPICS

Key articles

Diaz M, Neuhauser D (2004).
Lessons from using randomization to assess gold treatment for tuberculosis.

Boren SA (2006).
Max Pinner (1891-1948).
Boren SA, Diaz M, Neuhauser D (2006).
James Burns Amberson (1890-1979).
Moberg J, Kramer M (2015).
A brief history of the cluster randomized trial design.

Other articles

Klar N, Donner A (2004).
The impact of EF Lindquist’s 1940 text “Statistical Analysis in Educational Research” on cluster randomization.
Neuhauser D, Diaz M (2006).
Jesse GM Bullowa (1879-1943).
Bryder L (2014).
The Medical Research Council and treatments for tuberculosis before streptomycin.

All topics

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