ARTICLES — COMMENTARIES

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Hróbjartsson A, Gøtzsche PC, Gluud C (1988).
The controlled clinical trial turns 100 years: Fibiger’s trial of serum treatment of diphtheria. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Armitage P† (2002).
Randomisation and alternation: a note on Diehl et al. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Olsen SF (2002).
The People’s League of Health trial. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Loudon I (2002).
The use of historical controls and concurrent controls to assess the effects of sulphonamides, 1936-1945. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Chalmers I, Clarke M (2002).
J Guy Scadding and the move from alternation to randomization. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Loudon I (2002).
An early Medical Research Council controlled trial of vitamins for preventing infection. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2003).
Withering’s 1785 appeal for caution when reporting on a new medicine. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Dean ME (2003).
‘An innocent deception’: placebo controls in the St Petersburg homeopathy trial, 1829-30. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2003).
Edward Alanson 1782: responsibility in surgical innovation. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2003).
MacLean 1818: comparing like with like and recognising ethical double standards in therapeutic experimentation. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2003).
James Lind at Haslar Hospital 1758-1774: a methodological theorist. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2003).
James Lind and the evaluation of clinical practice. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Gong Y, Gluud C (2003).
Commentary on the Ben Cao Tu Jing (11th century). Atlas of Materia Medica. Song Dynasty (960-1279). JLL Bulletin: Commentaries on the history of treatment evaluation.

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Vandenbroucke JP (2003).
Thalidomide: an unanticipated adverse effect. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Vandenbroucke JP (2003).
The contribution of William Fletcher’s 1907 report to finding a cause and cure for beriberi. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2003).
John Clark 1780 & 1792: learning from properly kept records. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Vandenbroucke JP (2003).
Aspirin: an unanticipated beneficial effect. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2003).
James Lind and scurvy: 1747 to 1795. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Doll R (2003).
Controlled trials testing two or more treatments simultaneously. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Armitage P† (2003).
Some recollections of the early years of the Medical Research Council (MRC) Statistical Research Unit. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Gøtzsche PC (2004).
Niels Finsen’s treatment for lupus vulgaris. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Kaptchuk TJ (2004).
Early use of blind assessment in a homeopathic scientific experiment. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Diaz M, Neuhauser D (2004).
Lessons from using randomization to assess gold treatment for tuberculosis. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Klar N, Donner A (2004).
The impact of E.F. Lindquist’s text “Statistical Analysis in Educational Research” on cluster randomisation. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Hampton J (2004).
An early parallel group trial in cardiology. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Morabia A (2004).
Pierre-Charles-Alexandre Louis and the evaluation of bloodletting. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Lee MR (2004).
The miracle of St. Alfege’s: discovering a treatment for myaesthenia gravis. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Cochrane AL, Blythe M (2004).
Sickness in Salonica. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Houston C (2004).
Ferguson’s BCG research – Canada’s first randomized clinical trial? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Stoll S (2004).
Paul Martini’s Methodology of therapeutic investigation. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Clarke M (2004).
The 1944 patulin trial of the British Medical Research Council: an example of how concerted common purpose can get reliable answers to important questions very quickly. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Elwood P (2004).
The first randomized trial of aspirin for heart attack and the advent of systematic overviews of trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Bastian H (2004).
Down and almost out in Scotland: George Orwell, tuberculosis and getting streptomycin in 1948. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Sutton G (2004).
James Lind aboard Salisbury. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Donaldson IML (2004).
Ambroise Paré’s accounts of new methods for treating gunshot wounds and burns. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Donaldson IML (2005).
Mesmer’s 1780 proposal for a controlled trial to test his method of treatment using ‘Animal Magnetism’. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Hemminki E (2005).
Commentary on an early placebo controlled trial in Finland. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Huth EJ (2005).
Quantitative evidence for judgments on the efficacy of inoculation for the prevention of smallpox: England and New England in the 1700s. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Pollock JI (2005).
Two controlled trials of supplementary feeding of British school children in the 1920s. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tibi S (2005).
Al-Razi and Islamic medicine in the 9th Century. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Volmink J (2005).
The willow as a Hottentot (Khoikhoi) remedy for rheumatic fever. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Spanager L (2005).
Jansen’s 1910 use of a single blind experiment to assess the effects of radioactive water on rheumatic diseases. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Jefferson T (2006).
Why the MRC randomized trials of whooping cough (pertussis) vaccines remain important more than half a century after they were done. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Huth EJ (2006).
Jules Gavarret’s Principes Généraux de Statistique Médicale: a pioneering text on the statistical analysis of the results of treatments. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Davey Smith G (2006).
Capitalising on Mendelian randomization to assess the effects of treatments. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Stolberg M (2006).
Inventing the randomized double-blind trial: The Nürnberg salt test of 1835. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Marks HM† (2006).
The Kendrick-Eldering-(Frost) pertussis vaccine field trial. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Nasser M, Tibi A (2006).
Ibn Hindu and the science of medicine. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Huth EJ (2006).
Transatlantic ideas on the philosophy of therapeutics in the middle of the 19th century. JLL Bulletin: Commentaries on the history of treatment evaluation.

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McPherson K, Bunker JP (2006).
Costs, risks and benefits of surgery: a milestone in the development of health services research. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Morabia A (2006).
Joseph Goldberger’s research on the prevention of pellagra. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Neuhauser D, Diaz M (2007).
Use of rotation to allocate patients to homeopathic or regular medical services in Cook County Hospital, Chicago, 1882. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Sinclair L (2007).
Recognising, treating and understanding pernicious anaemia. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Nasser M, Tibi A, Savage-Smith E (2007).
Ibn Sina’s Canon of Medicine: 11th century rules for assessing the effects of drugs. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Marks HM† (2007).
James Angus Doull and the well-controlled common cold. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Kerr CE, Milne I, Kaptchuk TJ (2007).
William Cullen and a missing mind-body link in the early history of placebos. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Morabia A (2007).
Claude Bernard, statistics, and comparative trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Neuhauser D, Diaz M, Chalmers I (2007).
A puzzling omission in a great medical textbook edited by a pioneer of controlled trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Louis-Courvoisier M (2007).
An 18th century controlled trial prompted by a potential shortage of hospital beds. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2007).
An early 18th century proposal for improving medicine by tabulating and analysing practice. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Stylianou C, Kelnar C (2008).
The introduction of successful treatment of diabetes mellitus with insulin. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Nunn JF (2008).
A treatment that has stood the test of time for over three and a half millennia. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Bracken MB (2008).
Why animal studies are often poor predictors of human reactions to exposure. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Gluud C, Hilden J (2008).
Povl Heiberg’s 1897 methodological study on the statistical method as an aid in therapeutic trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Boylston AW, Williams AE (2008).
Zabdiel Boylston’s evaluation of inoculation against smallpox. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Huth EJ (2008).
The move toward setting scientific standards for the content of medical review articles. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Joosse NP, Pormann PE (2008).
Archery, mathematics, and conceptualising inaccuracies in medicine in 13th century Iraq and Syria. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Podolsky SH (2008).
Jesse Bullowa, specific treatment for pneumonia, and the development of the controlled clinical trial. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Middleton J (2008).
Pellagra and the blues song ‘Cornbread, meat and black molasses’. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Shannon H (2008).
A statistical note on Karl Pearson’s 1904 meta-analysis. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Boylston AW (2008).
William Watson’s use of controlled clinical experiments in 1768. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Rennie D, Chalmers I (2009).
Exposing the dangers to patients of medical reviews and textbooks that ignore scientific principles. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Cox DR (2009).
Randomization for concealment. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Wessely S (2009).
Surgery for the treatment of psychiatric illness: the need to test untested theories. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Hytten F (2009).
Isabella Leitch’s contributions to the development of systematic reviews of research evidence. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Furberg CD (2009).
How should one analyse and interpret clinical trials in which patients don’t take the treatments assigned to them? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Adams CE (2009).
James Crichton Browne and controlled evaluation of drug treatment for mental illness. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Williams KJ (2009).
The introduction of ‘chemotherapy’ using arsphenamine – the first magic bullet. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Moore W (2009).
John Hunter: learning from natural experiments, ‘placebos’, and the state of mind of a patient in the 18th century. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Chalmers I, Toth B (2009).
19th century controlled trials to test whether belladonna prevents scarlet fever. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Dean ME (2009).
Comparative evaluation of homeopathy and allopathy within the Parisian hospital system, 1849-51. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Armitage P† (2009).
A statistical note on the analysis of the 1948 MRC streptomycin trial. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Peters L, Hepner J (2009).
George Chalmers’ portrait of James Lind, 1783-2008: a reconstruction. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2010).
Towards endocrinology: Theodor Kocher’s 1883 account of the unexpected effects of total ablation of the thyroid. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Morabia A (2010).
Edward Jenner’s 1798 report of challenge experiments demonstrating the protective effects of cowpox against smallpox. JLL Bulletin: Commentaries on the history of treatment evaluation.

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JLL Bulletin Editors (2010).
Commentary on Rapport général sur les prix décernés en 1862. Mémoires de l’Académie Impériale de Médecine XXVI, Paris: Ballière, p xxii-xxxv. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Chalmers I (2010).
Joseph Asbury Bell and the birth of randomized trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Chalmers I (2010).
Why the 1948 MRC trial of streptomycin used treatment allocation based on random numbers. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Boylston AW (2010).
Thomas Nettleton and the dawn of quantitative assessments of the effects of medical interventions. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Löwy I (2010).
Martin Arrowsmith’s clinical trial: scientific precision and heroic medicine. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2010).
Adolf Bingel’s blinded, controlled comparison of different anti-diphtheritic sera in 1918. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Edwards M (2010).
Dora Colebrook and the evaluation of light therapy. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Gluud C (2010).
Danish contributions to the evaluation of serum therapy for diphtheria in the 1890s. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Bryder L (2010).
The Medical Research Council and clinical trial methodologies before the 1940s: the failure to develop a ‘scientific’ approach. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Farewell V, Johnson A† (2010).
The first British textbook of medical statistics. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Slater SD (2010).
The discovery of thyroid replacement therapy. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Opinel A, Gachelin G (2010).
French 19th century contributions to the development of treatments for diphtheria. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Spain P, Kadan-Lottick N (2010).
Observations of unprecedented remissions following novel treatment for acute leukemia in children in 1948. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Cook H (2010).
Testing the effects of Jesuit’s bark in the Chinese Emperor’s court. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Doyle D (2011).
Thomas MacLagan’s 1876 demonstration of the dramatic effects of salicin in rheumatic fever. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Maehle A-H (2011).
Four early clinical studies to assess the effects of Peruvian bark. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Podolsky SH, Davey Smith G (2011).
Park’s story and Winters’ tale: alternate allocation clinical trials in turn of the Century America. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Ferroni E, Jefferson T, Gachelin G (2011).
Angelo Celli and research on the prevention of malaria in Italy a century ago. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Boylston AW (2011).
Observation and experimentation in developing ‘the Suttonian Method’ of inoculation. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Wickenden JVS (2011).
The strange disappearances of James Lind. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Solis C (2011).
Bartolomé Hidalgo de Agüero’s 16th century, evidence-based challenge to the orthodox management of wounds. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Fox DM (2011).
Systematic reviews and health policy: the influence of a project on perinatal care since 1988. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Birbeck E (2011).
The Royal Hospital Haslar: from Lind to the 21st century. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Chalmers I, Dukan E, Podolsky SH, Davey Smith G (2011).
The advent of fair treatment allocation schedules in clinical trials during the 19th and early 20th centuries. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Gartlehner G, Stepper K (2011).
Julius Wagner-Jauregg: pyrotherapy, Simultanmethode, and ‘racial hygiene’. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Farewell V, Johnson A† (2011).
The origins of Austin Bradford Hill’s classic textbook of medical statistics. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Vandenbroucke JP (2012).
Adolphe Vorderman’s 1897 study on beriberi: an example of scrupulous efforts to avoid bias. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Mann H, Djulbegovic B (2012).
Comparator bias: why comparisons must address genuine uncertainties. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Cockerill A, Goble PJ (2012).
Thomas Graham Balfour, pioneering medical statistician and stern disciplinarian. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Boylston AW (2012).
The origins of inoculation. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Campbell MJ (2012).
Doing clinical trials large enough to achieve adequate reductions in uncertainties about treatment effects. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tsiompanou E, Marketos SG† (2012).
Hippocrates: timeless still. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Marušić A, Fatović-Ferenčić S (2012).
Adoption of the double dummy trial design to reduce observer bias in testing treatments. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Sidebottom E (2012).
Roger Bacon and the beginnings of experimental science in Britain. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Boylston AW (2012).
The origins of vaccination: no inoculation, no vaccination. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Boylston AW (2012).
John Haygarth’s 18th century ‘Rules of Prevention’ for eradicating smallpox. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Loudon I (2013).
Ignaz Phillip Semmelweis’ studies of death in childbirth. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Donaldson IML (2013).
Francis Bacon’s comments on the power of negative observations in his Novum Organum, first published in 1620. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Sugiyama Y, Seita A (2013).
Kanehiro Takaki and the control of beriberi in the Japanese Navy. JLL Bulletin: Commentaries on the history of treatment evaluation.

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La Rochelle P, Julien A-S (2013).
How dramatic were the effects of handwashing on maternal mortality observed by Ignaz Semmelweis? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Pormann PE (2013).
Qualifying and quantifying medical uncertainty in 10th century Baghdad: Abu Bakr al-Razi. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Gachelin G (2013).
The interaction of scientific evidence and politics in debates about preventing malaria in 1925. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Chalmers I (2013).
UK Medical Research Council and multicentre clinical trials: from a damning report to international recognition. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2013).
William Cheselden’s 1740 presentation of data on age-specific mortality after lithotomy. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Bryder L (2014).
The Medical Research Council and treatments for tuberculosis before streptomycin. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Dean ME (2014).
The mustard gas experiments done by the British Homoeopathic Society for the Ministry of Home Security, 1941-42. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Oliver S (2014).
Advantages of concurrent preparation and reporting of systematic reviews of quantitative and qualitative evidence. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Milne I, Chalmers I (2014).
Alexander Lesassier Hamilton’s 1816 report of a controlled trial of bloodletting. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Bird SM (2014).
The 1959 meeting in Vienna on controlled clinical trials – a methodological landmark. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2014).
Statistics and the British controversy about the effects of Joseph Lister’s system of antisepsis for surgery, 1867-1890. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Moberg J, Kramer M (2015).
A brief history of the cluster randomized trial design. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Hampton J (2015).
Therapeutic fashion and publication bias: the case of anti-arrhythmic drugs in heart attack. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Toth B (2015).
Why the MRC Therapeutic Trials Committee didn’t introduce controlled clinical trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Straus S, Eisinga A, Sackett D† (2015).
What drove the Evidence Cart? Bringing the library to the bedside. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Schlesselman JJ (2015).
Jerome Cornfield’s Bayesian approach to assessing interim results in clinical trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Wager E (2015).
Good Publication Practice 3: reflections on becoming a guideline grandmother. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Dean ME (2015).
Selective suppression by the medical establishment of unwelcome research findings: The cholera treatment evaluation by the General Board of Health, London 1854. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Burton MJ (2015).
Astley Cooper’s dramatically effective treatment of deafness. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Donaldson IML (2016).
Petrarch’s letter to Boccaccio ‘on the proud and presumptuous behaviour of physicians’. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Howick J (2016).
Aulus Cornelius Celsus and ‘empirical’ and ‘dogmatic’ medicine JLL Bulletin: Commentaries on the history of treatment evaluation.

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Donaldson IML (2016).
George Starkey’s 1658 challenge to Galenists to compare their treatment results with his. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Donaldson IML (2016).
van Helmont’s proposal for a randomised comparison of treating fevers with or without bloodletting and purging. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Peto J (2016).
Reflections on the importance of strict adherence to treatment protocols: acute lymphoblastic leukaemia in children in the 1970s in the US and the UK. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Peto R (2016).
Reflections on the design and analysis of clinical trials and meta-analyses in the 1970s and 1980s. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Donaldson IML (2016).
Antoine de Lavoisier’s role in designing a single-blind trial to assess whether ‘Animal Magnetism’ exists. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Zwarenstein M (2016).
‘Pragmatic’ and ‘Explanatory’ attitudes to randomized trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Lechuga RI, Castro AC (2016).
Dramatic effects of control measures on deaths from yellow fever in Havana, Cuba, in the early 1900’s. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Treasure T (2016).
Documenting the dramatic effects of operative treatment of mitral stenosis. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Donaldson IML (2016).
Reflections on translating passages on ‘empirical’ and ‘dogmatic’ medicine in Celsus’s De medicina. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Senn SJ (2017).
Cushny and Peebles, optical isomers, and the birth of modern statistics. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Chalmers J, Chalmers I, Tröhler U (2017).
Helping physicians to keep abreast of the medical literature: Andrew Duncan and Medical and Philosophical Commentaries, 1773-1795. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Farewell V, Johnson A† (2017).
Major Greenwood and clinical trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Treasure T (2017).
Turning blue babies pink: Alfred Blalock’s shunt for Fallot’s Tetralogy. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Altman DG† (2017).
Avoiding bias in trials in which allocation ratio is varied. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Goodman NW (2017).
John Shaw Billings: creator of Index Medicus and medical visionary. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Glasziou P, Aronson JK (2017).
A brief history of clinical evidence updates and bibliographic databases JLL Bulletin: Commentaries on the history of treatment evaluation.

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La Rochelle P (2017).
Using randomized, double-blind, n-of-1 trials of food challenge to diagnose food allergy and assess the effectiveness of food allergen avoidance. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Pollock JI (2017).
A controlled trial using a factorial design reported in 1946. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Bailey R, Howick J (2018).
Did John Stuart Mill influence the design of controlled clinical trials? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Toth B (2018).
Pioneering controlled trials of treatments for erysipelas and pneumonia in Glasgow, 1936-47. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Schulz KF, Chalmers I, Altman DG†, Grimes DA, Moher D, Hayes RJ (2018).
‘Allocation concealment’: the evolution and adoption of a methodological term. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Weingarten S (2018).
Food in Daniel 1:1-16: the first report of a controlled experiment? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Garattini S (2018).
Italian controlled trials to assess prevention and treatment of malaria, 1900-1930s. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tognoni G, Franzosi MG, Garattini S (2018).
Embedding patient- and public health-oriented research in a national health service: the GISSI experience. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Pormann PE (2018).
Concepts of patient groups in 10th-century Iraq and Persia JLL Bulletin: Commentaries on the history of treatment evaluation.

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Bird A (2018).
James Jurin and the avoidance of bias in collecting and assessing evidence on the effects of variolation. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Marson Smith P, Colquhoun D, Chalmers I (2019).
John Henry Gaddum’s 1940 guidance on controlled clinical trials JLL Bulletin: Commentaries on the history of treatment evaluation.

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Meinert C† (2019).
The trials and tribulations of the University Group Diabetes Program: lessons and reflections. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Bishop D, Gill E (2019).
Robert Boyle on the importance of reporting and replicating experiments. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Jefferson T (2019).
Sponsorship bias in clinical trials – growing menace or dawning realisation? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Matthews RAJ (2020).
The origins of the treatment of uncertainty in clinical medicine. Part 2: the emergence of probability theory and its limitations. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2020)
Probabilistic thinking and the evaluation of therapies, 1700-1900. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Welsh BC, Podolsky SH, Zane SN (2020).
Between medicine and criminology: Richard Cabot’s contribution to the design of experimental evaluations of social interventions in the late 1930s. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Williams AN, O’Dell FJ, Aronson JK (2020).
Was William Harvey’s commitment to experimentation reflected in his clinical practice? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Matthews RAJ (2020).
The origins of the treatment of uncertainty in clinical medicine. Part 1: Ancient roots, familiar disputes. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Glasziou PP, Tikkinen KAO (2021).
The RECOVERY trial platform: a milestone in the development and execution of treatment evaluation during an epidemic. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Senn SJ, Chalmers I (2021).
Giving and taking: ethical treatment assignment in controlled trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Brinkmann R, Podolsky SH (2021).
The ‘Personal Equation’ as observer bias, and proposed methods to contain it in Anglo-American medicine. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Clarke M (2021).
The true meaning of DICE: Don’t Ignore Chance Effects JLL Bulletin: Commentaries on the history of treatment evaluation.

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Gøtzsche PC (2021).
Citation bias: questionable research practice or scientific misconduct? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Held L, Matthews RAJ (2022).
Paradigm lost: Carl Liebermeister and the development of modern medical statistics. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Ritskes-Hoitinga M, Pound P (2022).
The role of systematic reviews in identifying the limitations of preclinical animal research, 2000 – 2022. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Podolsky SH (2022).
The (Harry) Gold Standard: angina, suggestion, and the path to the “double-blind” test and Clinical Pharmacology. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Glasziou P, Matthews R, Boutron I, Chalmers I, Armitage P† (2023)
The differences and overlaps between ‘explanatory’ and ‘pragmatic’ controlled trials: a historical perspective. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Chalmers I, Matthews R, Glasziou P, Boutron I, Armitage P† (2023).
Analysis of clinical trial by Treatment Allocated or by Treatment Received? Applying ‘the intention-to-treat principle’. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Nylenna, M (2023).
Paul Owren, Christopher Bjerkelund and the dawn of controlled trials in Norway. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Kirakosian R, Möllenbrink L, Zamore G, Kaptchuk TJ, Jensen K (2023).
Heresy, witchcraft, Jean Gerson, scepticism, and the use of placebo controls. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Senn S (2024).
An Early 20th Century Handbook on ‘Meta-analysis’: David Brunt’s The Combination of Observations. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Clarke M, Chalmers I, Alderson P, Hopewell S (2024).
Reports of randomised control trials (RCTs) should begin and conclude with up-to-date systematic reviews of other relevant trials: a 25-year audit of the quality of trial reports. JLL Bulletin: Commentaries on the history of treatment evaluation.

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