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Illustrating the development of fair tests of treatments in health care
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ADDITIONAL METHODS - ANALYSIS BIAS
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Montori VM, Devereaux PJ, Adhikari NK, Burns KE, Eggert CH, Briel M, Lacchetti C, Leung TW, Darling E, Bryant DM, Bucher HC, Schunemann HJ, Meade MO, Cook DJ, Erwin PJ, Sood A, Sood R, Lo B, Thompson CA, Zhou Q, Mills E, Guyatt GH (2005)
Randomized trials stopped early for benefit: a systematic review. JAMA 294:2203-2209.
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Trotta F, Apolone G, Garattini S, Tafuri G (2008)
Stopping a trial early in oncology: for patients or for industry? Annals of Oncology Feb 29; doi:10.1093/annonc/mdn042.
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Kramer MS, Martin RM, Sterne JA, Shapiro S, Mourad D, Platt RW (2009)
The double jeopardy of clustered measurement and cluster randomisation. BMJ 339:503-505.
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Bassler D, Briel M, Montori VM, Lane M, Glasziou P, Zhou Q, Heels-Ansdell D, Walter SD, Guyatt GH; STOPIT-2 Study Group (2010)
Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA. 303:1180-7.
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methods
Principles of testing
Pre-clinical
Dramatic effects
N-of-1 crossover
Crossover tests
Cluster allocation
Factorial design
Double dummy
Placebo effects