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Illustrating the development of fair tests of treatments in health care
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ADDITIONAL METHODS - PRE-CLINICAL
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Hooijmans CR, Tillema A, Leenaars M, Ritskes-Hoitinga M (2010)
Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed. Laboratory Animals 44:170-175
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Hooijmans CR, IntHout J, Ritskes-Hoitinga M, Rovers MM (2014)
SYRCLE's risk of bias tool for animal studies. BMC Medical Research Methodology. 14:43.
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methods
Principles of testing
Pre-clinical
Dramatic effects
N-of-1 crossover
Crossover tests
Cluster allocation
Factorial design
Double dummy
Placebo effects