Quiz: Why treatment comparisons must address genuine uncertainties

JLL Quiz 2.1

Why comparisons must address genuine uncertainties

Multiple-choice questions for Chapter 2.1 of The James Lind Library’s Introduction to Fair Tests of Treatments

Prepared by Mike Clarke.

1 / 5

Should researchers do a systematic review before starting a new study of a treatment?

No, they should simply start the study as soon as possible

No, because they know best

No, because this might lose their competitive advantage

Yes, to check if uncertainties about the treatment have already been resolved

2 / 5

What were the consequences of researchers continuing to do placebo-controlled trials of antibiotics for people having bowel surgery after the 1970s?

Patients in the placebo groups were denied an effective form of care

Patients entering the trials had a fair chance of getting the best treatment

Uncertainties about the effectiveness of antibiotics for patients having bowel surgery were resolved

Antibiotics were proved to be no better than placebos

3 / 5

What did a Dutch review of animal studies of calcium-blocking drugs show?

That the drugs prevented infection after surgery

That the drugs would be an effective treatment for people after a stroke

That there was no evidence from the animal studies that the drugs would be useful for humans

That the drugs reduced the risk of death from cancer

4 / 5

What characteristic(s) might be found in unfair tests of a treatment?

Using an inappropriate dose for the comparator treatment, only

Following patients for too short a time, only

Using outcome measures that have little or no relation to what matters to patients, only

Using an inappropriate dose for the comparator treatment, following patients for too short a time and measuring outcomes that are not relevant to patients

5 / 5

How have some Research Ethics Committees failed to protect patients recruited to clinical trials?

By requiring researchers seeking approval for new trials to have reviewed existing evidence systematically

By not requiring researchers seeking approval for new trials to have reviewed existing evidence systematically

By ensuring that there is a genuine need for a new trial

By requiring researchers to obtain informed consent from trial participants

Your score is

The average score is 90%

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Illustrating the development of fair tests of treatments in health care

Why comparisons must address genuine uncertainties

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James Lind LibraryIllustrating the development of fair tests of treatments in health care