Nettleton T (1722)
Part of a letter from Dr. Nettleton, physician at Halifax, to Dr. Jurin, R. S. Sec concerning the inoculation of the small pox, and the mortality of that distemper in the natural way. Philosophical Transactions of the Royal Society of London (1722-1723) 32:209-212.
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Benjamin Franklin’s (1706-1790) place in the history of medicine.
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William Watson’s use of controlled clinical experiments in 1768.
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Zabdiel Boylston’s evaluation of inoculation against smallpox.
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Edward Jenner’s 1798 report of challenge experiments demonstrating the protective effects of cowpox against smallpox.