INTERVENTIONS — DRUG

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Ben Cao Tu Jing (11th century)
Atlas of Materia Medica. Song Dynasty (960-1279).

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Stuart, James, King of Great Britaine, France and Ireland (1616)
A counterblaste to tobacco. In: The workes of the most high and mightie prince, James Published by James, Bishop of Winton, and Deane of his Majesties Chappel Royall. London: printed by Robert Barker and John Bill, printers to the Kings most excellent Majestie, pp 214-222.

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de Fontaney F (1703)
Letter to F de la Chaise, from Cheu-Chan (a port in the Province of ‘Chekian’), dated 15 February. In: Lettres Édifiantes Et Curieuses, Écrites Des Missions Étrangères Par Quelques Missionnaires De La Compagnie De Jesus [Edifying and curious letters, written from the foreign missions by some missionaries of the Company of Jesus]. 34 vols. Paris: Chez Nicolas le Clerc, rue Saint Jacques, à l’Image Saint Lambert, 1703-1776. Vol. 7 (1707): pp. 234-244.

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Berkeley G (1752)
Farther thoughts on tar-water. In: Bishop of Cloyne. A miscellany, containing several tracts on various subjects. London: Tonson and Draper.

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Repertoire du Regi[s]tre CC (1761)
Maladies Vénériennes, et la Chambre Noble [Venereal diseases, and the City Council]. Archives d’Etat de Genève, Arch. Hosp. Aa 104, 18 janvier, p 53, and 6 décembre, pp 135-6.

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Lind J (1763)
Two papers on fevers and infection. London: D Wilson.

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Stone E (1764)
An account of the success of the bark of the willow in the cure of agues. Philosophical Transactions 53:195-200.

View

Lind J (1771)
An essay on diseases incidental to Europeans in hot climates. London: Becket and De Hondt.

View

Society of Gentlemen in Scotland (1771)
Medicine. Encyclopaedia Britannica. Vol 1. Edinburgh: Bell & Macfarquhar, pp 630-632.

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Gregory J (1772)
Lectures on the duties and qualifications of a physician. London: Strahan and Cadell. (new ed.) Edinburgh: Creech.

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Sims J (1774)
A discourse on the best methods of prosecuting medical enquiries. London: J Johnson, p78-9, 80, 86-88, 99-101.

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Millar J (1777)
Observations on the practice in the medical department of the Westminster General Dispensary. London, by order of the Governors.

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Dobson M (1779)
A medical commentary on fixed air. Chester: J. Monk.

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Millar J (1779)
Observations on the management of the prevailing diseases particularly in the Army and Navy. London, for the author.

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Home F (1780)
Clinical experiments, histories and dissections. Edinburgh: Creech; London: Murray.

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McCausland R (1783)
Facts and observations on different medical subjects. Medical Commentaries viii (1781/82), 247-96.

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Fowler T (1785)
Medical reports of the effects of tobacco in the cure of dropsies and dysuries.... London: J Johnson.

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Withering W (1785)
An account of the foxglove and some of its medical uses: with practical remarks on dropsy and other diseases. London: J and J Robinson.

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Fowler T (1786)
Medical reports of the effects of arsenic in the cure of agues, remitting fevers and periodic headachs. London: J Johnson, pp 105-107.

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Parry CH (1786)
Experiments relative to the medical effects of Turkey Rhubarb, and of the English Rhubarbs, No. I and No. II made on patients of the Pauper Charity. Letters and Papers of the Bath Society 11:431-453.

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Hunter J (1788)
A treatise on the venereal disease. London: G Nicol and J Johnson, pp 69-70.

View

Black W (1789)
An arithmetical and medical analysis of the diseases and mortality of the human species. London: J Johnson.

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Robertson R (1789)
Observations on jail, hospital, or ship fever. New ed. London: for the Author.

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Robertson R (1790)
Essay on fever. London: printed for the author.

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Sims RC (1791)
Letter VI. Letters and Papers of the Bath Society III: 486-487.

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Clark J (1792)
Observations on the diseases which prevail in long voyages to hot countries. London: J Murray.

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Ferriar J (1792)
Medical histories and reflections. Vol 1. London: Cadell and Davies.

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Fordyce G (1793)
An attempt to improve the evidence of medicine. Transactions of a Society for the Improvement of Medical and Chirurgical Knowledge.  London: J Johnson.

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Rowley W (1793)
The causes of a great number of deaths amongst adults and children. 2nd edn. London: Newbery.

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Ferriar J (1795)
Medical histories and reflections. Vol. 2. London: Cadell and Davies.

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Millar J (1798)
Observations on the management of diseases in the Army and Navy in reply to Dr. Monroe. London: for the Author.

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Rollo J (1801)
A short account of the Royal Artillery Hospital at Woolwich. London: Mawman.

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Fordyce G (1802)
A second dissertation on fever. London: J Johnson.

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Haygarth J (1805)
A clinical history of diseases 1. Acute rheumatism. 2. Nodosity of the joints. London: Cadell and Davies.

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Sutton T (1806)
A practical account of remittent fever. London: Robinson, p 16-17.

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Warren J (1812)
Remarks on Angina Pectoris. New England Journal Medicine & Surgery 1:1-11.

View

Blane G (1813)
Observations on the comparative prevalence, mortality, & treatment of different diseases.... Medico-chirurgical Transactions, Vol 4, p 89-141, London.

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MacGrigor J (1816)
Sketch of the medical history of the British armies in the peninsula of Spain and Portugal, during the late campaigns. Medico-chirurgical Transactions 6:381-489.

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MacLean C (1818)
Results of an Investigation, respecting Epidemic and Pestilential Diseases. Vol. 2. London: Underwood.

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Double FJ (1820)
Considérations thérapeutiques sur une nouvelle préparation de quinquina. Revue médicale, 6ème livraison.

View

Elliotson J (1823)
Medical properties of quinine. Medico-Chirurgical Transactions 12:543-564.

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Magendie F (1829)
Formulaire pour la préparation et l'emploi de plusieurs médicaments. Paris, imprimerie de Plassan,1ère édition.

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Bigelow J (1835)
A discourse on self-limited diseases, delivered before the Massachusetts Medical Society at their annual meeting, May 27, 1835. Boston: Nathan Hale p 8-10.

View

Forbes J (1846)
Homoeopathy, allopathy and “young physic”. British and Foreign Medical Review 225-265.

View

Thomson TRH (1846)
On the value of quinine in African remittent fever. Lancet 47:244-245.

View

Bryson A (1847)
Report on the Climate and Principal Diseases of the African Station. London: Printed by order of the Lords Commissioners of the Admiralty.

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Bryson A (1854)
On the prophylactic influence of quinine. Medical Times and Gazette 8:6-7.

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Balfour TG (1854)
Quoted in West C. Lectures on the Diseases of Infancy and Childhood. London, Longman, Brown, Green and Longmans, p 600.

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Treatment Committee of the Medical Council (1855)
Report on the results of the different methods of treatment pursued in epidemic cholera. [Metropolitan Report and Report on the Provinces throughout England and Scotland]. Report to the General Board of Health. London: Her Majesty’s Stationery Office.

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McShane C (1856)
Medical Statistical Returns of the African Station. In: Statistical Report of the Health of the Royal Navy for the year 1856. London: House of Commons, pp 82-83.

View

Baikie WB (1856)
Narrative of an exploring voyage up the rivers Kwora and Binue in 1854. London: John Murray.

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Thompson T (1859)
Observations on the administration of ozonized oils. Medical and Chirurgical Transactions 42:349-360.

View

Holmes OW (1861)
Currents and countercurrents in medical science with other addresses and essays. Boston: Ticknor and Fields, 1861.

View

Béclard PA (1863)
Rapport général sur les prix décernés en 1862 [General report on the prizes awarded in 1862]. Mémoires de l’Académie Impériale de Médecine XXVI, Paris: Ballière, pp. xxii-xxxv.

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Barclay AW (1864)
Medical errors: fallacies connected with the application of the inductive method of reasoning to the science of medicine. London: Churchill, p 55 and 71-73.

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Liebreich O (1869)
Das Chloral, ein neues Hypnoticum und Anaesthetikum [Chloral, a new hypnotic and anaesthetic]. Berliner Klinische Wochenschrift 6:325-327.

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Crichton Browne J (1872)
Conium in the treatment of acute mania. Lancet 1:217-8.

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Maclagan T (1876)
The treatment of acute rheumatism by salicin. Lancet 1:383-84.

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Hartridge G (1886)
Tobacco amblyopia. BMJ 1:200.

View

Fry HD (1887)
The value of the antiseptic method in obstetric practice and its application to the forceps operation. JAMA 8:388-390.

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Boxall, cited in Williams J (1888)
On the effect of ergot on the involution of the uterus. BMJ 1:229.

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Stuart W (1889)
A remarkable case of morphine addiction. BMJ 1:1051-52.

View

Phillips J (1890)
On the analgesic value of antipyrin intra - and post - partum. Lancet 2:605-607.

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Andrew J (1891)
Harveian Oration. London: Adlard and Son. p 16-19.

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Dymock W, Warden CJH, Hooper D (1891)
A history of the principal drugs of vegetable origin met with in British India. Pharmacographia Indica Vol. II. London: Kegan Paul, Trench, Trübner, pp 180-181.

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Priestley J (1895)
On the value of eucalyptus oil as a disinfectant in scarlet fever. Lancet 1:861-863.

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Heiberg P (1897)
Studier over den statistiske undersøgelsesmetode som hjælpemiddel ved terapeutiske undersøgelser [Studies on the statistical study design as an aid in therapeutic trials]. Bibliotek for Læger 89:1-40.

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Anonymous (1899)
Echoes and news: the chlorine treatment of diphtheria. Medical News 74:403.

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Williams FH (1899)
Scarlatina. Reports of societies. Boston Medical And Surgical Journal 141:348.

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Koch R (1900)
Vierter Bericht über die Thätigkeit der Malaria-Expedition, die Monate März und April 1900 umfassend [Fourth report on the activity of the Malaria Expedition, comprising the months of March and April 1900] Deutsche medicinische Wochenschrift 25:397-398.

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Waters EE (1903)
Malaria as seen in the Andamans penal settlement. Lancet 1:1657-62.

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Celli A (1903)
La malaria in Italia durante il 1902. Parte II: Profilassi della malaria. [Malaria in Italy in 1902. Part II: Prophylaxis of Malaria]. Annali di Igiene Sperimentale 13:322-343.

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Cousin M (1905)
Des éruptions consecutives aux injections de sérum antidiphthérique et de leur traitement prophylactique par l’ingestion de clorure de calcium. Thèse pour le Doctorat en médicine. Paris : Jules Rousset, 36-44.

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Cushny AR, Peebles AR (1905)
The action of optical isomers. II. Hyoscines. J Physiology 32:501-510.

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Netter A (1906)
Efficacité de l’ingestion de chlorure de calcium comme moyen préventif des éruptions consecutives aux injections de sérum [Effect of the ingestion of calcium chloride for preventing eruptions following serum injections]. Séances et Mémoires de la Société de Biologie 58:279-280.

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Drake DJ (1907)
The treatment of dysentery by yellow santonine. Journal of Tropical Medicine and Hygiene 10:351-352.

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Gewin J (1908)
Chlorkalzium gegen die Serumkrankheit [Calcium chloride against serum sickness]. Muenchener Medizinische Wochenshcrift 50:2670-2671.

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Rivers WHR (1908)
The influence of alcohol and other drugs on fatigue. London: Edward Arnold.

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Anonymous (1908)
Alcohol in the treatment of pneumonia and enteric fever. Lancet 157:442.

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Alt K (1909)
Behandlungsversuche mit Arsenophenylglyzin bei Paralytikern [Treatment experiments with arsenophenylglycine in paralytics]. Muenchener Medizinische Wochenschrift 56:1457-1459.

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Döderlein D (1910)
The origin and prevention of puerperal fever. BMJ 2:1222-24.

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Wechselmann W (1910)
Über die Behandlung der Syphilis mit Dioxydiamido-arseno-benzol [On the treatment of syphilis with dioxy-diamido-arseno-benzol]. Berliner Klinische Wochenschrift 47:1261-1264.

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Hollingworth HL (1911)
The influence of caffeine on mental and motor efficiency. Archives of Psychology/Columbia Contributions to Philosophy and Psychology 20:iii-v

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Solis-Cohen M, Strickler A (1911)
The effect produced by some therapeutic measures on the different forms of leucocytes in pulmonary tuberculosis. New Enlgand Journal of Medicine 165:563-568.

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McDonagh JER (1912)
Salvarsan in syphilis and allied diseases. Oxford: Oxford Medical Publications.

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Hewlett AW (1913)
Clinical effects of “natural” and “synthetic” sodium salicylate. JAMA 61:319-321.

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Council on Pharmacy and Chemistry (1913)
Sinkina. JAMA 61:1056-1058.

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Carver AE (1914)
Pneumosan in the treatment of pulmonary tuberculosis. Lancet 2:372-373.

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Baer JL (1915)
Scopolamin-morphin treatment in labor. JAMA 64:1723-1728.

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Bastedo WA (1915)
Clinical Experience with Liquid Paraffin (Liquid Petrolatum): A Comparative Investigation Made Under the Auspices of the Council on Pharmacy and Chemistry. JAMA 64: 808-809.

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Plass ED (1916)
Post partum care of perineum. Bulletin of Johns Hopkins Hospital 27:107-109.

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Council on Pharmacy and Chemistry (1917)
Biniodol. JAMA 68: 650-51.

View

Avata AA, Woodyatt RT (1918)
Treatment of facial erysipelas at Camp Cody, N.M. JAMA 71:900-01.

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Bleuler E (1919)
Das Autistisch-Undisziplinierte Denken in der Medizin und Seine Überwindung [Autistic-undisciplined thinking in medicine and how to overcome it]. Berlin: Springer.

View

Leighton Kesteven H (1919)
A study of epidemic influenza in Australia. Lancet 2:1189-91.

View

Marine D, Kimball OP (1920)
The prevention of simple goiter in man: fourth paper. Archives of Internal Medicine 25:661-72.

View

Acton HW (1920)
Researches on the treatment of benign tertian fever. Lancet 1:1257-1261.

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Medical Research Council (1925)
Report of the committee upon cinchona derivatives and malaria. In: Clinical comparisons of quinine and quinidine. London: HMSO, pp 5-16.

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Swellengrebel NH (1925)
A summary of the more important facts on adult anophelines and their larvae observed by us or brought to our notice duing our tour through eastern Europe and Italy (May-September 1924). pp183-190. In: Malaria Commission of the Health Organisation (1925). Report on its tour of investigation in certain European countries in 1924. Geneva: League of Nations. C.H. 273.

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Diehl HS (1925)
Value of Chlorin in the treatment of colds. JAMA 84:1629-32.

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Fletcher W (1925)
The relative efficiency of quinine and quinidine in the treatment of malaria. In: Medical Research Council. Clinical comparisons of quinine and quinidine. London: Her Majesty's Stationery Office, pp 17-27.

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Malaria Commission of the Health Organisation (1925)
Report on its tour of investigation in certain European countries in 1924. Geneva: League of Nations. C.H. 273.

View

Moir JC (1925)
Comparison of the narcotic effects of the two hyoscines (scopolomaines). BMJ 2:514-515.

View

Maier HW (1926)
L’ergotamine, inhibiteur du sympathique étudié en clinique, comme moyen d’exploration et comme agent thérapeutique. Revue Neurologique. 1:1104 (June).

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Mauel W (1926)
Ist das Omnadin bei kruppöser Pneumonie wirksam [Is Omnadin effective in pneumonia with croup]? Münchener Medizinische Wochenschrift 73:652.

View

Sinton JA (1926)
Studies in Malaria, with special reference to Treatment. Part I. Introduction and routine methods. Indian Journal of Medical Research 13: 565-577.

View

Sinton JA (1926)
Studies in Malaria, with special reference to treatment. Part II. The effects of treatment on the prevention of relapse in infections with Plasmodium Falciparum. Indian Journal of Medical Research 13: 579-601.

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Sinton JA (1927)
Studies in Malaria, with special reference to treatment. Part VII. The intravenous injection of sodium stovarsol in the treatment of benign tertian malaria. Indian Journal of Medical Research 15:287-299.

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Earp JR (1927)
The need for reporting negative results. JAMA 88:119.

View

Harris KE (1927)
Series of cases of auricular fibrillation treated with quinidine sulphate. Heart 14:283-288.

View

Freeman J (1929)
Discussion on the action and use of ephedrine. Proceeding of Royal Society of Medicine 22:1369.

View

Pearce RM (1929)
The treatment of influenza with S.U.P. 36. BMJ 2:663-666.

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Sinton JA, Bird W (1929)
Studies in Malaria, with special reference to treatment. Part XI: The Cinchona alkaloids in the treatment of benign tertian malaria. Indian Journal of Medical Research 16: 725-746.

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Kauders O (1930)
Ueber Nachbehandlung nach Malariatherapie [On the management of patients after malaria therapy]. Deutsche Medizinishe Wochenshcrift 61:400-401.

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Lewis T (1930)
Angina pectoris associated with high blood pressure and its relief by amyl nitrate. Heart 14:305-327.

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Wyckoff J, DeGraaf AC, Parent S (1930)
Influence of salicylates on the heart in rheumatic fever. American Heart Journal 5:568-573.

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Wyckoff J, Du Bois EF, Woodruff IO (1930)
The therapeutic value of digitalis in pneumonia. JAMA 95:1243-1249.

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Amberson JB, McMahon BT, Pinner M (1931)
A clinical trial of sanocrysin in pulmonary tuberculosis. American Review of Tuberculosis 24:401-435.

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Davis WE (1931)
The incidence of untoward symptoms following the intravenous injection of sodium tetraiodophenolphthalein in cholecystography. New England Journal of Medicine 205:534-6.

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Friend GE (1931)
Amidopyrin in measles. BMJ 1:33.

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Manson-Bahr P (1931)
Modern methods of treatment of intestinal amœbiasis. Proceedings of Royal Society of Medicine 24:1538–1548.

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Roos H (1931)
Behandling av kruppös pneumoni med kininjektioner [Treatment of acute pneumonia with quinine injections]. Finska Läkaresällskapets Handlingar 73:778-789.

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King D (1931)
Prevention of post-operative pulmonary complications. Report and Notices of Meetings. The New England Journal of Medicine 205:1320.

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Sanders JP, Dawson, WT (1932)
Efficacy of quinidine in malaria. JAMA 99:1773-7.

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Borovsky MP, Steigmann F (1933)
Amidopyrine in the treatment of measles. JAMA 100:1859-61.

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Diehl HS (1933)
Medicinal treatment of the common cold. JAMA 101:2042-2049.

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Evans W, Hoyle C (1933)
The comparative value of drugs used in the continuous treatment of angina pectoris. Quarterly Journal of Medicine 7:311-338.

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Bray GW, Witts LJ (1934)
Pseudo-ephedrine in asthma. Lancet 1:788-90.

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Evans W, Hoyle C (1934)
The prevention and treatment of individual attacks of angina pectoris (angina of effort). Quarterly Journal of Medicine 3:105-135.

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Walker MB (1934)
Treatment of myasthenia gravis with physostigmine. Lancet 1:1200-1201.

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Hediger E, Gold H (1935)
USP ether from large drums and ether from small cans labeled ‘For Anesthesia’. JAMA 104:2244-2448.

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Lennox WG, Von Storch TJC (1935)
Experiences with ergotamine tartrate in 120 patients with migraine. JAMA 105:169-171.

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Robin L, Van-Huan T (1935)
Essais comparés de prophylaxie médicamenteuse en région hyperendémique par la praequine et la quinine ou la quinacrine [Comparative trials of anti-malarial drug prophylaxis in a hyperendemic area with præquine, associated with quinine or quinacrine]. Bulletin de la Société de Pathologie exotique 28:650-658.

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Hicks EP, Diwan Chand S (1935)
The relative clinical efficacy of totaquina and quinine. In: Records of the Malaria Survey of India 5:39-50.

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Colebrook L, Kenny M (1936)
Treatment of human puerperal infections, and of experimental infections in mice, with prontosil. Lancet 1:1279-1286.

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Colebrook L, Kenny M (1936)
Treatment with prontosil of puerperal infections due to haemolytic streptococci. Lancet 2:1319-1322.

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Curphey TJ, Solomon S (1936)
The therapeutic value of calcium salts in serum sickness. New England Journal of Medicine 214:150-153.

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Moir JC (1936)
Clinical experiences with the new alkaloid, ergometrine. BMJ 2:799-801.

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O’Sullivan ME (1936)
Termination of 1000 attacks of migraine with ergotamine tartrate. JAMA 107:1208-1212.

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Sutliff WD (1936)
Adequate tests of curative therapy in man. Annals of Internal Medicine 1936-1937;10:89-97.

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Bastianelli G, Mosna E, Canalis A (1937)
Prevention and treatment of malaria by synthetic drugs. Bulletin of the Health Organisation of the League of Nations 6:822-891.

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Colebrook L, Purdie AW (1937)
Treatment of 106 cases of puerperal fever by sulphanilamide. Lancet 2:1237-1242 & 1291-1294.

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Field JW, Niven JC, Hodgkin EP (1937)
The prevention of malaria in the field by the use of quinine and atebrine. Bulletin of the Health Organisation of the League of Nations 6:236-290.

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Gold H, Kwit NT, Otto H (1937)
The xanthines (theobromine and aminophyllin) in the treatment of cardiac pain. JAMA 108;2173-2179.

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Hesseltine HC (1937)
Evaluation by controlled series of vaginal trichomoniasis therapies. JAMA 109:768-71.

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Hogarth JC (1937)
Para-benzylaminobenzene-sulphonamide in the treatment of scarlet fever. BMJ 2:1160-1162.

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Parrot A, Catanei A, Ambialet R, Clastrier J (1937)
Comparative experiments in mass prophylaxis of malaria by means of quinine and synthetic drugs (quinacrine and praequine). Bulletin of the Health Organization of the League of Nations 6:685-765.

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Peters BA, Cullum IM (1937)
Post-scarlatinal nephritis: a study in prevention. BMJ 1:1020-21.

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Peters BA, Havard RV (1937)
Chemotherapy of streptococcal infections with p-bezylamino-benzene-sulphonamide. Lancet 1:1273-4.

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Snodgrass WR, Anderson T (1937)
Prontosil in the treatment of erysipelas: a controlled series of 312 cases. BMJ 2:101-104.

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Snodgrass WR, Anderson T (1937)
Sulphanilamide in the treatment of erysipelas: a controlled series of 270 cases. BMJ 2:1156-9.

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Wilbur DL, MacLean AR, Allen EV (1937)
Clinical observations on the effect of Benzedrine sulphate. JAMA 109:549-54.

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Malaria Commission (1937)
The treatment of Malaria: Study of synthetic drugs, as compared with Quinine, in the therapeutics and prophylaxis of Malaria. Bulletin of the Health Organisation, Vol VI, no. 6.

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Riseman JEF, Brown MG (1937)
Medicinal treatment of angina pectoris. Archives of Internal Medicine 60:100-118.

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Bahnsen P, Jacobsen E, Thesleff H (1938)
Studien über die Wirkung von beta-phenyl-isopropylaminsulfdat (Mecodrin) auf normale Menschen. [Studies on the effect of beta-phenyl-isopropylaminsulfdat (Mecodrin) on normal volunteers]. Klinische Wochenschrift 17:1074-1078.

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Evans GM, Gaisford WF (1938)
Treatment of pneumonia with 2-(p-aminobenzene sulphonamido) pyridine. Lancet 2:14-19.

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Gaudin HJ, Zide HA, Thompson GJ (1938)
Use of sulfanilamide after transurethral prostatectomy. JAMA 110:1887-90.

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Johnstone RW (1938)
Prophylactic use of sulphonamide preparations in obstetric practice. BMJ 1:562-64.

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Schwentker FF, Waghelstein J (1938)
A note on the use of sulfanilamide in scarlet fever. Baltimore Health News 15:41-44.

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Snodgrass WR, Anderson T, Rennie JL (1938)
Sulphamido-chrysoidine, sulphanilamide, and benzylsulphanilamide in the treatment of erysipelas. BMJ 2:399-403.

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Bowie FJ (1938)
Chemotherapy in gonorrhoea: a preliminary report on the use of 2-(p-aminobenzenesulphonamido)pyridine, M & B 693. BMJ 2:283-284.

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Anderson T (1939)
Sulphanilamide in the treatment of measles. BMJ 1:716-718.

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Banks HS (1939)
Chemotherapy of meningococcal meningitis. Lancet 2:921-927.

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Benn EC (1939)
Sulphanilamide in the treatment of scarlet fever. BMJ 2:644-646.

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Cutts M, Gormly CF, Burgess AM (1939)
The treatment of lobar pneumonia with sulfapyridine. New England Journal of Medicine 221:263-266.

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Dub LA, Lurie LA (1939)
Use of benzedrine in the depressed phase of the psychotic state. Ohio State Medical Journal 35:39-45.

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Evans W, Loughman O (1939)
The drug treatment of hyperpiesia. British Heart Journal 1:199-228.

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Farnworth Anderson T, Dowdeswell RM (1939)
Treatment of pneumonia with M. & B. 693. Lancet 1:252-255.

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Graham D, Warner WP, Dauphinée JA, Dickson RC (1939)
The treatment of pneumococcal pneumonia with Dagenan (M&B 693). Canadian Medical Association Journal 40:325-332.

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Master AM, Jaffe HL, Dack S (1939)
The drug treatment of angina pectoris due to coronary artery disease. American Journal of Medical Science 197:774-782.

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Pasricha CL, de Monte AJH, Chatterjee BC, Mian AS (1939)
Treatment of cholera (A note on the results of treatment by different methods). Indian Medical Gazette 74:400-401.

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Price AE, Myers GB (1939)
Treatment of pneumococcic pneumonia with sulfanilamide. JAMA 112:1021-7.

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Don CSD, Luxton RW, Donald HR, Ramsay WA, Macartney DW, Stewart Smith G, Adderley CH (1940)
Treatment of pneumonia with M&B 693. Lancet 1:311-4.

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French JO, Hooker ML, Vause RB, Robinson AL (1940)
Dental anaesthesia in children: a comparision of vinyl ether and ethyl chloride in a series of 200 cases. BMJ 2:432-435.

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Gaddum JH (1940)
Pharmacology. London: Oxford University Press 378-383.

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Gaisford WF, Whitelaw W (1940)
Sulphathiazole in treatment of pneumococcal lobar pneumonia. Lancet 2:451-452.

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Gregory KK, West EJ, Stevens RE (1940)
Epidemic cerebrospinal meningitis (meningococcic): the treatment of 113 patients with antimeningococcus serum, meningococcus antitoxin and sulfanilamide. JAMA 115:1091-5.

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Jordan JH, Blakelock, Johnston WR (1940)
Treatment of cerebrospinal fever with suphapyridine. BMJ 1:1005-1008.

View

Menten ML, Macdonald RR, Brönykovsky N (1940)
Treatment of pneumonia by sulfapyridine and by hydroxyethylapocupreine dihydrochloride. American Journal of Diseases of Children 59:497-508.

View

Rhoads PS, Afremow ML (1940)
Sulfanilamide in treatment of sore throat due to hemolytic streptococci: with controls. JAMA 114:942-3.

View

Sidell N, Abrams MI (1940)
Treatment of chronic arthritis. JAMA 144:1740-1742.

View

Abraham EP, Chain E, Fletcher CM, Gardner AD, Heatley NG, Jennings AM, Florey HW (1941)
Further observations on penicillin. Lancet 2:177-189.

View

Alstead S (1941)
Action of Bismuth Carbonate in gastric disease. Lancet 238: 420-423.

View

Anderson DEW, Cruickshank R (1941)
The treatment of bacilliary (Flexner) dysentery with sulphanilylguanidine. BMJ 2:497-501.

View

Cooper ML, Zucker RL, Wagoner S, Brown EW, Bennett R (1941)
Sulfathiazole for acute diarrhea and dysentery of infants and children. JAMA 117:1520-3.

View

Jones HB, Fairbrother RW (1941)
Sulphathiazole and sulphapyridine in acute gonorrhoea. Lancet 2:9-10.

View

Miller M (1941)
Benzedrine sulphate in the treatment of nicotinism. Medical Record 2:590-593.

View

Plummer N, Liebmann J, Solomon S, Kammerer WH, Kalkstein M, Ensworth HK (1941)
Chemotherapy versus combined chemotherapy and serum. JAMA 116:2366-2371.

View

Top FH, Young DC (1941)
The treatment of moderately severe scarlet fever: A study of alternate patients treated with sulfanilamide, convalescent serum and scarlet fever antitoxin. JAMA 117:2056-60.

View

Wagle PM, Sokhey SH, Dikshit BB, Ganapathy K (1941)
Chemotherapy in plague. Indian Medical Gazette 76:29-32.

View

Lipman Cohen E (1942)
Local treatment of impetigo with sulphonamide. BMJ 1:359.

View

People's League of Health (1942)
Nutrition of expectant and nursing mothers: interim report. Lancet 2:10-12.

View

Siegel M (1942)
Studies on the control of acute respiratory infections: preliminary report on the oral administration of sulfadiazine at the onset of acute respiratory illnesses. JAMA 119:783-5.

View

Florey ME, Florey HW (1943)
General and local administration of penicillin. Lancet 1:387.

View

Hopkins WA (1943)
Patulin in the common cold. IV: Biological properties: extended trial in the common cold. Lancet 2:630-635.

View

Lepper MH, Sweet LK, Dowling HF (1943)
The treatment of meningococcic infections with sulphadiazine and sulphamerazine. JAMA 123:134-138.

View

Morgan TN, Wylie-Smith R (1943)
Lobar pneumonia treated with sulphamezathine and sulphadiazine. Lancet 2:731-733.

View

Pulvertaft RJPV (1943)
Local therapy of war wounds: I with Penicillin (article 1 of 2). Lancet 2:341-36 and 379-384

View

Stuart-Harris CH, Francis AE, Stansfeld JM (1943)
Patulin in the common cold. Lancet 2:684.

View

Greenwood M (1943)
Statistical note. Lancet 2:634-5.

View

Van Winkle W, Herwick RF, Calvery HO, Smith A (1944)
Laboratory and clinical appraisal on new drugs. Report of the Council on Pharmacy and Chemistry. JAMA 126:958-961.

View

Anderson T (1944)
Clinical studies in sulphonamide chemotherapy. MD thesis, University of Glasgow.

View

Beattie J, Marshall J (1944)
Studies on hepatic dysfunction. II. The value of sulphur-containing amino-acids and casein digest in the prevention of post-arsphenamine jaundice. BMJ 2: 651-655.

View

Cecil RL, Plummer N, Smillie WG (1944)
Sulfadiazine in the treatment of the common cold. JAMA 124:8-14.

View

Coburn AF (1944)
The prevention of respiratory tract bacterial infections. JAMA 126:88-89.

View

Cutler EC (1944)
Discussion on Penicillin. Proceedings of Royal Society of Medicine 37: 101–12.

View

Dick A (1944)
Vaccines and chemotherapy in pneumococcal lobar pneumonia. Lancet 1:564-565.

View

Florey ME, Williams REO (1944)
Hand infections treated with penicillin. Lancet 1:73-81.

View

Fries ED (1944)
The treatment of tonsillitis with small doses of sulfonamides. JAMA 126:93-4.

View

Hinshaw HC, Feldman WH (1944)
Evaluation of therapeutic agents in clinical tuberculosis. American Review in Tuberculosis 50:202-213.

View

Holling HE, McArdle B, Trotter WR (1944)
Prevention of seasickness by drugs. Lancet 243:127-129.

View

Medical Research Council (1944)
Clinical trial of patulin in the common cold. Lancet 2:373-5.

View

Scadding JG (1944)
Comparative effects of sulphonamide drugs in mild bacillary dysentery. Lancet 1:784-786.

View

Stansfeld JM, Francis AE, Stuart-Harris CH (1944)
Laboratory and clinical trials of Patulin. Lancet 2:370-372.

View

Wright J, Cruickshank R, Gunn W (1944)
The control of dust-borne streptococcal infection in measles wards. BMJ 1:611-614.

View

Yeomans A, Snyder JC, Murray ES, Zarafonetis CJD, Ecke RS (1944)
The therapeutic efficacy of para-aminobenzoic acid in louse borne typhus fever. JAMA 126:349-56.

View

Fraser TN (1944)
Gold treatment in rheumatoid arthritis. Annals of Rheumatic Diseases. 4:71-75.

View

Mackenna RMB, Cooper-Willis ES (1945)
Impetigo contagiosa in the army, treated with microcrystalline sulphathiazole. Lancet 2:357-358.

View

Hill IGW, Guest AI (1945)
Prevention of sea-sickness in assault craft. BMJ 2:6–11.

View

Anderson T, Ferguson MS (1945)
Comparative effect of sulphonamide and penicillin in pneumonia. Lancet 2:805-808.

View

Fletcher RT, Scadding JG (1945)
Observations on the MI room treatment of “acute simple diarrhoea” with sulphaguanidine. Unpublished manuscript.

View

Scadding JG (1945)
Sulphonamides in bacillary dysentery. Lancet 2:549-553.

View

Wolman M, Omar M, Abu-Taimb M (1945)
Louse-borne relapsing fever treated with calcium gold keratinate. Lancet 2:775-777.

View

Wright J (1945)
Cross-infection risks in the hospitalization of measles patients. BMJ 1:285-289.

View

Christie RV (1946)
Penicillin in subacute bacterial endocarditis. Lancet 1:369.

View

Fatti L, Florey ME, Joules H, Humphrey JH, Sakula J (1946)
Acutely infected pleural effusions: techniques of penicillin treatment. Lancet 1:295-300

View

Goodman LS, Wintrobe MM, Dameshek W, Goodman MJ, Gilman A and McLennan MT (1946)
Nitrogen mustard therapy. Use of methyl-bis(beta-chloroethyl)amine hydrochloride and tris(beta-chloroethyl)amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders. Journal of the American Medical Association 132:126-132.

View

Jellinek EM (1946)
Clinical tests on comparative effectiveness of analgesic drugs. Biometric Bulletin 2:87-91.

View

Sher N (1946)
Delayed menstruation: causes and treatment. BMJ 1:347 – 349.

View

Tierney NA (1946)
Effect of para-aminobenzoic acid in Tsutsugamushi disease. JAMA 131:280-5.

View

Johnstone RDC (1946)
Relapsing benign tertian malaria treated with paludrine. Lancet 2:825-826.

View

Anderson T, Landsman JB (1947)
Oral penicillin in treatment of pneumonia in the adult. BMJ 2:950-953.

View

Bolton JH, Pivawer MJ (1947)
Faucial diphtheria among army personnel in Belgium, 1945. BMJ 2:373-376.

View

Furber Murphy A (1947)
Treatment of acute mastitis. BMJ 1:271.

View

Glickman I (1947)
The use of penicillin lozenges in the treatment of Vincent’s infection and other acute gingival inflammations. Journal of the American Dental Association 34:406-409.

View

Hirsh HL, Rotman-Kavka, G, Dowling HF, Sweet LK (1947)
Penicillin therapy of scarlet fever: comparison with antitoxin and symptomatic therapy. JAMA 133:657-61.

View

Johnstone RDC (1947)
Paludrine in relapsing benign tertian malaria: further trials. Lancet 1:674-675.

View

Mitchell GAG (1947)
The value of penicillin in surgery. BMJ 1:41-45.

View

Wills L, Hill G, Bingham K, Miall M, Wrigley J (1947)
Haemoglobin levels in pregnancy. The effect of the rationing scheme and routine administration of iron. British Journal of Nutrition 1:126-138.

View

Asher R (1948)
A method of testing analgesics. Lancet 2:771-3.

View

Bakst H, Kissin M, Leibowitz S, Rinzler S (1948)
The effects of intravenous aminophylline on the capacity of effort without pain in patients with angina of effort. American Heart Journal 36:527-534.

View

Bevan G, Evans R, Pugh I, Sudds MVN, Parker MT, Sladden AFS (1948)
Penicillin and sulphathiazole in typhoid fever: clinical trial. Lancet 1:545-550.

View

Christie RV (1948)
Penicillin in subacute bacterial endocarditis. BMJ 1:1-4.

View

Elovainio E, Östling G (1948)
Observations on preoperative treatment with strophanthin. Annales Chirurgiae et Gynaecologiae Fenniae 37:23-35.

View

Farber S, Diamond LK, Mercer RD, Sylvester RF, Wolff JA (1948)
Temporary remissions in acute leukaemia in children produced by folic acide antagonist, 4-aminopteroyl-glutamic acid (aminopterin). New England Journal of Medicine 238:787-793.

View

Jersild T (1948)
Penicillin therapy in scarlet fever and complicating otitis. Lancet 1:671-673.

View

Löfström G (1948)
Investigations on acute infections of the respiratory tract. IV. Experimental studies on the effect of small doses of sulphonamides in respiratory tract infections. Acta Medica Scandinavica 130:1-11.

View

Malchow-Møller M (1948)
Sulfathiazol og diazil. [sulphamethazine]. Ugeskrift for Læger 110:466-8.

View

Medical Research Council (1948)
Streptomycin treatment of tuberculous meningitis. Lancet 1:582-596.

View

Medical Research Council (1948)
Streptomycin treatment of pulmonary tuberculosis: a Medical Research Council investigation. BMJ 2:769-782.

View

Merk R (1948)
Die Stickstoffsenfgasbehandlung der Lymphogranulomatose [Nitrogen Mustard Treatment of Lymphogranulomatosis]. Medizinische Klinik 43:629-35.

View

Parsons CG (1948)
Penicillin and sulphonamides in typhoid fever: experience of physicians in military hospitals in the Middle East. Lancet 1:510-513

View

Sølling P (1948)
Lucamid – et nyt analgeticum. [Lycamid - a new analgesic] Ugeskrift for Læger 110:1473-5.

View

Thomas DV (1948)
Benzedrine, coramine and picrotoxin: a comparison. Anaesthesia 3:122-123.

View

War Office (1948)
Efficacy of therapeutic measures. In: Statistical Report on the Health of the Army, 1943-1945. London: Her Majesty's Stationary Office, p 273-294.

View

Wright IS, Marple CD, Beck DF (1948)
Report of the Committee for the Evaluation of Anticoagulants in the Treatment of Coronary Thrombosis with Myocardial Infarction. American Heart Journal 36:801-815.

View

Appelbaum E, Nelson J, Albin MB (1949)
The treatment of penumococcic meningitis with penicillin; a study of 125 consecutive cases, with 73% recovery. American Journal of Medicial Science 218:260-4.

View

Bignall JR, Crofton J (1949)
Antihistamine drugs in the treatment of nausea and vomiting due to streptomycin. BMJ 1:13-14.

View

Carliner PE, Radman HM, Gay LN (1949)
Treatment of nausea and vomiting of pregnancy with Dramamine – preliminary report. Science 110:215-216.

View

Harrison SH, Topley E, Lennard-Jones J (1949)
The value of systemic penicillin in finger pulp infections: a controlled trial of 169 cases. Lancet 1:425-430.

View

Marshall EK (1949)
Clinical therapeutic trial of a new drug. Bulletin of the Johns Hopkins Hospital 85:221-230.

View

Nitsch K (1949)
Ulcusleiden und vegetatives Nervensystem [Ulcer illness and the autonomic nervous system]. Medizinische Klinik 44:503-5.

View

Travell J, Rinzler SH, Bakst H, Benjamin ZH, Bobb AL (1949)
Comparison of effects of alpha-tocopherol and matching placebo on chest pain in patients with heart disease. Annals of the New York Academy of Sciences 52:345-53.

View

Daniels M (1950)
Scientific appraisement of new drugs in tuberculosis. American Review of Tuberculosis 61:751-756.

View

Greiner T, Gold H, Cattel M, Travell J, Bakst H, Rinzler SH, Benjamin ZH, Warshaw LJ, Bobb AL, Kwit NT, Modell W, Rothendler HH, Messeloff CR, Kramer ML (1950)
A method for the evaluation of the effects of drugs on cardiac pain in patients with angina of effort. American Journal of Medicine 9: 143 - 155.

View

Jacobs A, Borthwick WM (1950)
Streptomycin in urinary tuberculosis. Proceedings of the Royal Society of Medicine 43:453-466.

View

Long ER, Ferebee SH (1950)
A controlled investigation of streptomycin treatment in tuberculosis. Public Health Reports 65:1421-1451.

View

Medical Research Council (1950)
Clinical trials of antihistaminic drugs in the prevention and treatment of the common cold. BMJ 2:425-431.

View

Quin CA, Mason RM, Knowelden J (1950)
Clinical assessment of rapidly acting agents in rheumatoid arthritis. BMJ 2:810-813.

View

Reid DD (1950)
Statistics in clinical research. Annals of the New York Academy of Sciences 52:931-934.

View

Swedish National Association against Tuberculosis. Therapeutic Trials Committee (1950)
Para-aminosalicylic acid treatment in pulmonary tuberculosis. American Review of Tuberculosis 61:597-612.

View

Rinzler SH, Bakst H, Benjamin Z, Bobb AL, Travell J (1950)
Failure of alpha tocopherol to influence chest pain in patients with heart disease. Circulation 1:288-293.

View

Cartwright EW (1951)
Dramamine in nausea and vomiting of pregnancy. Western Journal of Surgery 59: 216-234.

View

Daniels M (1951)
Clinical evaluation of chemotherapy in tuberculosis. British Medical Bulletin 7:320-326.

View

Glaser EM, Hervey GR (1951)
The prevention of seasickness with hyoscine, Benadryl and Phenergan. Lancet 2:749-753.

View

Neuwirth I, Chilton NW (1951)
The clinical effectiveness of different concentrations of procaine for mandibular extractions. Oral Surgery, Oral Medicine and Oral Pathology 4:383-387.

View

Daniels M, Hill AB (1952)
Chemotherapy of pulmonary tuberculosis in young adults: An analysis of the combined results of three medical research council trials. BMJ 1:1162-1168.

View

Doll R, Pygott F (1952)
Factors influencing the rate of healing of gastric ulcers: admission to hospital, phenobarbitone, and ascorbic acid. Lancet 1: 171-175.

View

Fisher OD, Whitfield CR (1952)
Terramycin in the treatment of pneumonia in children. BMJ 2:864-865.

View

Nagpaul DR (1952)
Clinical trials with ‘Tibione’ in pulmonary tuberculosis. Indian Journal of Medicial Research 40:151-159.

View

Hogben L, Sim M (1953)
The self-controlled and self-recorded clinical trial for low grade morbidity. British Journal of Preventative and Social Medicine 7,163-179.

View

Rinzler SH, Travell J, Bakst H, Benjamin ZH, Rosenthal RL, Rosenfeld S, Hirsch BB (1953)
Effect of heparin in effort angina. American Journal of Medicine 14:438-447.

View

Conference on Therapy [Gold H] (1954)
How to evaluate a new drug. American Journal of Medicine 11:722-727.

View

Joint Committee of the Medical Research Council and Nuffield Foundation on Clinical Trials of Cortisone, A.C.T.H., and Other Therapeutic Measures in Chronic Rheumatic Diseases (1954)
A Comparison of Cortisone and Aspirin in the Treatment of Early Cases of Rheumatoid Arthritis. BMJ 1:1223-1227.

View

Kilpatrick GS, Oldham PD (1954)
Calcium chloride and adrenaline as bronchial dilators compared by sequential analysis. BMJ 2:1388-1391.

View

Miall WE, Oldham PD, Cochrane AL (1954)
The treatment of complicated pneumoconiosis with isoniazid. British Journal of Industrial Medicine 11:186-191.

View

Gaddum JH (1954)
Clinical pharmacology. Proceedings of the Royal Society of Medicine 47:195-204.

View

Hare EH (1955)
Comparative efficacy of hypnotics: a self-controlled, self-recorded clinical trial in neurotic patients. British Journal of Preventive and Social Medicine 9:140-146.

View

Straus B, Eisenberg J, Gennis J (1955)
Hypnotic effects of an anti-histamine – methapyrilene hydrochloride. Annals of Internal Medicine 42:574-582.

View

Rheumatic Fever Working Party of the Medical Research Council of GB and the subcommittee of principal investigators of the American Council on Rheumatic Fever and Congenital Heart Disease, American Heart Association. (1955)
Treatment of acute rheumatic fever in children; a co-operative clinical trial of A.C.T.H., Cortisone, and Aspirin. BMJ 1:555-574

View

Herdan G (1955)
Statistics of Therapeutic Trials. Amsterdam: Elsevier.

View

Newton DRL, Tanner JM (1956)
N-acetyl-para-aminophenol as an analgesic. A controlled clinical trial using the method of sequential analysis. BMJ 2:1096-9.

View

Snell ES, Armitage P (1957)
Clinical comparison of diamorphine and pholcodine as cough suppressants by a new method of sequential analysis. Lancet 1:860-862

View

Cole JO, Ross S, Bouthilet L, Freeman H, Bennett IF, Hoffman JL, Lehmann H (1957)
Recommendations for reporting studies of psychiatric drugs. Public Health Report 72:638–645.

View

Bjerkelund CJ (1957)
The effect of long-term treatment with dicoumarol in myocardial infarction. A controlled clinical study. Acta Med Scand Suppl 330:1-212.

View

Greiner T, Bross I, Gold H (1957)
A method for evaluation of laxative habits in human subjects. Journal of Chronic Diseases 6:244-255.

View

Kerr DNS, Davidson S (1958)
Gastrointestinal intolerance to oral iron preparations. Lancet 2:489-492.

View

Symposium on Clinical Trials RSM (1958)
Report of a meeting held at the Royal Society of Medicine, London on 25th April 1958.

View

Watkinson G (1958)
Treatment of ulcerative colitis with topical hydrocortisone hemisuccinate sodium. A controlled trial employing restricted sequential analysis. BMJ 2:1077-82.

View

Doll R (1959)
Practical problems of drug trials in clinical practice. Lawrence DR, ed. Quantitative methods in human pharmacology and therapeutics. Oxford: Pergamon Press, pp. 213-221.

View

Greenhouse SW (1959)
Discussion following Kramer M, Greenhouse SW. Determination of sample size and selection of cases. In: Cole JO, Gerard RW (eds). Psychopharmacology. Problems in Evaluation. National Academy of Sciences, Publication 583, Washington DC, p 371.

View

Kety S (1959)
Comment. In: Cole JO, Gerard RW (eds). Psychopharmacology. Problems in Evaluation. National Academy of Sciences, Publication 583, Washington DC, p 651-652.

View

Oldham PD (1959)
Clinical and field trials. Acta Medica Hungarica 14:313-326.

View

Robertson JD, Armitage P (1959)
Report of a clinical trial to compare two hypotensive agents. Anaesthesia 14:53-64.

View

Waife SO, Shapiro AP (1959)
The clinical evaluation of new drugs. New York: Hoeber-Harper.

View

Witts LJ (1959)
Medical surveys and clinical trials: some methods and applications of group research in medicine. Oxford: Oxford University Press.

View

Zubrod CG, Schneiderman M, Frei E, Brindley C, Gold GL, Shnider B, Oviedo R, Gorman J, Jones R, Jonsson U, Colsky J, Chalmers T, Ferguson B, Dederick M, Holland J, Selawry O, Regelson W, Lasagna L, Owens AH (1960)
Appraisal of methods for the study of chemotherapy in man: Comparative therapeutic trial of nitrogen mustard and thiophosphoramide. Journal of Chronic Diseases 11:7-33.

View

McBride WG (1961)
Thalidomide and congenital abnormalities. Lancet 2:1358.

View

Comstock GW (1962)
Isoniazid prophylaxis in an undeveloped area. American Review of Respiratory Diseases 86:810-822.

View

Truelove SC, Watkinson G, Draper G (1962)
Comparison of corticosteroid and sulphasalazine therapy in ulcerative colitis. BMJ 2:1708-1711.

View

Glick BS, Margolis R (1962)
A study of the influence of experimental design on clinical outcome in drug research. American Journal of Psychiatry 118:1087-1096.

View

Glick BS (1963)
Inadequacies in the reporting of clinical drug research. Psychiatr Q 37:234-44.

View

Percy JS, Stephenson P, Thompson M (1964)
Indomethacin in the treatment of rheumatic diseases. Annals of Rheumatic Diseases 28:157-162.

View

Mahon WA, Daniel EE (1964)
A method for the assessment of reports of drug trials. Canadian Medical Association Journal 90:565-9.

View

Dudley Hart F, Boardman PL (1965)
Indomethacin and phenylbutazone: a comparison. BMJ 2:1281-1284.

View

Wechsler H, Grosser GH, Greenblatt M (1965)
Research evaluating antidepressant medications on hospitalized mental patients: A survey of published reports during a five-year period. The Journal of Nervous and Mental Disease 141(2):231-239.

View

Horwitz O, Payne PG, Wilbek E (1966)
Epidemiologic basis for tuberculosis eradication. 4. The isoniazid trial in Greenland. Bulletin of the World Health Organisation 35:509-526.

View

Schneiderman MA (1966)
Therapeutic trials in cancer. Working paper prepared for WHO Expert Committee on Cancer Treatment, Geneva, Switzerland, 9-15 March 1965. WHO/CANC/66.66.

View

Armitage P, Borchgrevink CF (1966)
Prevention of recurrences of myocardial infarction. Comments on a previous article. Archives of Internal Medicine 118:270-274.

View

Smith A, Traganza E, Harrison G (1969)
Studies on the effectiveness of antidepressant drugs. Psychopharmacol Bulletin (suppl) 1-53.

View

Wright V, Walker WC, McGuire RJ (1969)
Indomethacin in the treatment of rheumatoid arthritis. Annals of Rheumatic Diseases 28:157-162.

View

Doll R (1969)
Recognition of unwanted effects of drugs. BMJ 2:69-76.

View

Ley HL (1969)
Antibiotic drugs: procedural and interpretive regulations. Federal Register Vol. 34, No. 180, pp14596-597.

View

International Anticoagulant Review Group (1970)
Collaborative analysis of long-term anti-coagulant administration after acute myocardial infarction. Lancet 1:203-209.

View

Cornfield J (1971)
The University Group Diabetes Program: a further statistical analysis of the mortality findings. JAMA 217:1676-87.

View

Storey J, Rossi-Espagnet A, Mandel SPH, Matsushima T, Lietaert P, Thomas D, Brøgger S, Duby C, Gramiccia G (1973)
Sulfalene with pyrimethamine and chloroquine with pyrimethamine in single-dose treatment of Plasmodium falciparum infections. Bulletin of the World Health Organisation 49: 275-282.

View

Boston Collaborative Drug Surveillance Group (1974)
Regular aspirin intake and acute myocardial infarction. BMJ 1:440-443.

View

Elwood PC, Cochrane AL, Burr ML, Sweetnam PM, Williams G, Welsby E, Hughes SJ, Renton R (1974)
A randomized controlled trial of acetyl salicylic acid in the secondary prevention of mortality from myocardial infarction. BMJ 1:436-440.

View

Horwitz O, Magnus K (1974)
Epidemiologic evaluation of chemoprophylaxis against tuberculosis. American Journal of Epidemiology 99:333-342.

View

Medico-Pharmaceutical Forum (1974)
A report by the Forum’s Working Party on Clinical Trials. London: Medico-Pharmaceutical Forum.

View

Assaf RA, Dundee JW, Gamble JA (1975)
The influence of the route of administration on the clinical action of diazepam. Anesthesia 30:152-8.

View

Chalmers TC (1975)
Effects of ascorbic acid on the common cold. An evaluation of the evidence. Amer J Med 58:532-6.

View

Dürrigl T, Vitaus, Pucar I, Miko M (1975)
Diclofenac sodium (Voltaren): results of a multicentre comparative trial in adult-onset rheumatoid arthritis. Journal of International Medical Research 3:139-44.

View

Davis JM (1975)
Overview: Maintenance therapy in Psychiatry: I. Schizophrenia. American Journal of Psychiatry 132:1237-1244.

View

Rogers SC, Clay PM (1975)
A statistical review of controlled trials of imipramine and placebo in the treatment of depressive illnesses. British Journal of Psychiatry 127:599-603.

View

Conn HO, Blitzer BL (1976)
Nonassociation of adrenocorticosteroid therapy and peptic ulcer. New England Journal of Medicine 294(9):473-9.

View

Harding SM, Heath S (1976)
Intranasal steroid aerosol in perennial rhinitis: comparison with an antihistamine compound. Journal of Clinical Allergy 6:369-72.

View

Davis JM (1976)
Overview: Maintenance therapy in psychiatry:2. Affective disorders. American Journal of Psychiatry 133:1-13.

View

Beaver WT, Feise GA (1977)
A comparison of the analgesic effect of oxymorphone by rectal suppository and intramuscular injection in patients with postoperative pain. Journal of Clinical Pharmacology 17:276-91.

View

Chalmers TC, Matta RJ, Smith H, Kunzler A-M (1977)
Evidence favoring the use of anticoagulants in the hospital phase of acute myocardial infarction. New England Journal of Medicine 297:1091-96.

View

Chodak GW, Plaut ME (1977)
Use of systemic antibiotics for prophylaxis in surgery. A critical review. Archives of Surgery 112:326-334.

View

Christensen E, Juhl E, Tygstrup N (1977)
Treatment of duodenal ulcer. Randomized clinical trials of a decade (1964 to 1974). Gastroenterology 73:1170-1178.

View

Colombo F, Shapiro S, Slone D, Tognoni G (1977)
Epidemiological evaluation of drugs. Amsterdam: Elsevier/North-Holland Biomedical Press.

View

Gam F, Helles A, Andersen B (1977)
Hormonal treatment of climacteric complaints. A controlled, double-blind comparative study between 2 different types of sequential estrogen-gestagen preparations [in Danish]. Ugeskr Laeger 139:2808-12.

View

Jick H (1977)
The discovery of drug-induced illness. New England Journal of Medicine 296:481-485.

View

Murphy JE (1977)
A comparative trial of Anafranil, Pertofran and an Anafranil/Pertofran combination. Journal of International Medical Research 5(1 Suppl):16-23.

View

Wettrell K (1977)
Intraocular pressure reduction during treatment with pilocarpine and systemic propranolol. A comparative double-masked study. Albrecht Von Graefes Arch Klin Exp Ophthalmol 204:1-7.

View

The Association of the British Pharmaceutical Industry (1977)
Guidelines for preclinical and clinical testing of new medicinal products: Part 2 – investigations in man. London: ABPI.

View

The Association of the British Pharmaceutical Industry (1977)
Guidelines for preclinical and clinical testing of new medicinal products: Part 1-Laboratory investigations. London: ABPI.

View

Conn HO (1978)
Steroid treatment of alcoholic hepatitis. The yeas and nays [editorial]. Gastroenterology 74(2 Pt 1):319-322.

View

Donald JF, Molla AL (1978)
A controlled study comparing a three times daily dose of chlordiazepoxide with a single night-time dose of Trancopal in the control of anxiety, using a double-blind, double-dummy technique. J Int Med Res 6:105-10.

View

Hemminki E, Starfield B (1978)
Prevention and treatment of premature labour by drugs: review of controlled clinical trials. British Journal of Obstetrics and Gynaecology 85:411-417.

View

Jick H, Vessey M (1978)
Case-control studies in the evaluation of drug-induced illness. American Journal of Epidemiology 1978;107:1-7.

View

Rhind VM, Leatham PA, Wright V, Akbar FA, Downie WW (1978)
A comparative study of floctafenine (Idarac) and ibuprofen in the treatment of osteoarthrosis. Journal of International Medicial Research 2:11-13.

View

The Pooling Project Research Group (1978)
Relationship of blood pressure, serum cholesterol, smoking habit, relative weight and ECG abnormalities to incidence of major coronary events: Final report of the Pooling Project. Journal of Chronic Diseases 31:210-306.

View

Winship DH (1978)
Cimetidine in the treatment of duodenal ulcer: Review and commentary. Gastroenterology 74:402-406.

View

Blohmé G, Waldenström J (1979)
Glibenclamide and glipizide in maturity onset diabetes. A double-blind cross-over study. Acta Medica Scandinavica 206:263-7.

View

Mirakhur RK, Dundee JW, Connolly JD (1979)
Studies of drugs given before anaesthesia. XVII: anticholinergic premedicants. British Journal of Anesthesia 51:339-45.

View

Coronary Drug Project Research Group (1980)
Influence of adherence to treatment and response of cholesterol on mortality in the coronary drug project. New England Journal of Medicine 303:1038-41.

View

Editorial (1980)
Aspirin after myocardial infarction. Lancet 1:1172-3.

View

Hemminki E (1980)
Study of information submitted by drug companies to licensing authorities. BMJ 280:833-6.

View

Baum ML, Anish DS, Chalmers TC, Sacks HS, Smith H, Fagerstrom RM (1981)
A survey of clinical trials of antibiotic prophylaxis in colon surgery: Evidence against further use of no-treatment controls. New England Journal of Medicine 305:795-799.

View

DeSilva RA, Hennekens CH, Lown B, Cassells W (1981)
Lignocaine prophylaxis in acute myocardial infarction: An evaluation of randomised trials. Lancet 17:855-858.

View

Hemminki E (1981)
Quality of reports of clinical trials submitted by the drug industry to the Finnish and Swedish control authorities. European Journal of Clincal Pharmacology 19:157-165.

View

Loeliger EA (1981)
Oral anticoagulation in the secondary prevention of myocardial infarction. Acta Medica Scandinavica 651(suppl):305-315.

View

Polk BF (1981)
Antimicrobial prophylaxis to prevent mixed bacterial infection. Journal of Antimicrobial Chemotherapy 8(suppl D):115-129.

View

Andrews G, MacMahon SW, Austin A, Byrne DG (1982)
Hypertension: comparison of drug and non-drug treatments. BMJ 284:1523-1526.

View

Baber NS, Lewis JA (1982)
Confidence in results of beta-blocker postinfarction trials. BMJ 284: 1749-1750.

View

Cone LA (1982)
A survey of prospective, controlled clinical trials of gentamicin, tobramycin, amikacin, and netilmicin. Clinical Therapeutics 5:155-1621.

View

Editorial (1982)
Long-term and short-term beta-blockade after myocardial infarction. Lancet 1:1159-1161.

View

Hampton JR (1982)
Should every survivor of a heart attack be given a beta-blocker? Part I Evidence from clinical trials. BMJ 285:33-36.

View

Kavale K (1982)
The efficacy of stimulant drug treatment for hyperactivity: A metaanalysis. Journal of Learning Disabilities 15:280-289.

View

Lewis JA (1982)
Beta-blockade after myocardial infarction- a statistical view. Br J Clin Pharmac 14:15S-21S.

View

Robert E, Guibaud P (1982)
Maternal valproic acid and congenital neural tube defects. Lancet 2:937.

View

Stampfer MJ, Goldhaber SZ, Yusuf S, Peto R, Hennekens CH (1982)
Effect of intravenous streptokinase on acute myocardial infarction: pooled results from randomized trials. New England Journal of Medicine 307:1180-1182.

View

Venning GR (1982)
Validity of anecdotal reports of suspected adverse drug reactions: the problem of false alarms. BMJ 284:249-254.

View

May GS, Eberlein KA, Furberg CD, Passamani ER, DeMets DL (1982)
Secondary prevention after myocardial infarction: A review of long-term trials. Progress in Cardiovascular Diseases 24:331–352.

View

Baber NS, Lewis JA (1983)
Beta-adrenoreceptor blockade and myocardial infarction: When should treatment start and for how long should it continue? Circulation 67(suppl I):I-71-I-75.

View

Canner PL (1983)
Aspirin in coronary heart disease. Comparison of six clinical trials. Israel Journal of Medical Sciences 19:413-423.

View

Foon KA, Smalley RV, Riggs CW, Gale RP (1983)
The role of immunotherapy in acute myelogenous leukemia. Arch Intern Med 143: 1726-1731

View

Furberg CD, Bell RL (1983)
Effect of beta-blocker therapy on recurrent nonfatal myocardial infarction. Circulation 67 (suppl I): I-83-I-85.

View

Huitfeldt B, Montgomery SA (1983)
Comparison between zimeldine and amitriptyline of efficacy and adverse symptoms~a combined analysis of four British clinical trials in depression. Acta Psychiatr Scand (suppl) 308:55-69.

View

Leizorovicz A, Boissel JP (1983)
Oral anticoagulant in patients surviving myocardial infarction. A new approach to old data. European Journal of Clinical Pharmacology 24:333-336.

View

Messer J, Reitman D, Sacks HS, Smith H, Chalmers TC (1983)
Association of adrenocorticosteroid therapy and peptic-ulcer disease. The New England Journal of Medicine 309(1):21-24.

View

Moskowitz G, Chalmers TC, Sacks HS, Fagerstrom RM, Smith H Jr (1983)
Deficiencies of clinical trials of alcohol withdrawal. Alcoholism 7:42-46.

View

Thurber S, Eugene Walker C (1983)
Medication and hyperactivity: A meta-analysis. The Journal of General Psychology 108:79-86.

View

Yusuf S, Sleight P (1983)
Limitation of myocardial infarct size. Present status. Drugs 25:441-450.

View

Bassan MM, Shalev O, Eliakim A (1984)
Improved prognosis during long-term treatment with beta-blockers after myocardial infarction: Analysis of randomized trials and pooling of results. Heart Lung 13:164-168.

View

Gehlbach SH, Wilkinson WE, Hammond WE, Clapp NE, Finn AL, Taylor WJ, Rodell M (1984)
Improving drug prescribing in a primary care practice. Medical Care 22:193-201.

View

King JF, Keirse MJNC, Grant A, Chalmers I (1985)
Tocolysis - the case for and against. In: Beard RW, Sharp F, eds. Preterm Labour and its Consequences. London: Royal College of Obstetricians and Gynaecologists, 1985:199-208.

View

Kornitzer M, Rose G (1985)
WHO European Collaborative Trial of multifactorial prevention of coronary heart disease. Preventive Medicine 14:272-8.

View

Sacks HS, Chalmers TC, Berk AA, Reitman D (1985)
Should mild hypertension be treated? An attempted meta-analysis of the clinical trials. Mount Sinai Journal of Medicine 52:265-270.

View

Yusuf S, Peto R, Lewis J, Collins R, Sleight P (1985)
Beta blockade during and after myocardial infarction: an overview of the randomized trials. Progress in Cardiovascular Disease 27:335-371.

View

Gracely RH, Dubner R, Deeter WR, Wolskee PJ (1985)
Clinicians’ expectations influence placebo analgesia. Lancet 325:43. DOI:https://doi.org/10.1016/S0140-6736(85)90984-5

View

ISIS-1 (first International Study of Infarct Survival) Collaborative Group (1986)
Randomised trial of intravenous atenolol among 16 027 cases of suspected acute myocardial infarction: ISIS-1. First International Study of Infarct Survival Collaborative Group. Lancet 2:57-66.

View

Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico (GISSI) (1986)
Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet 1: 397-402.

View

Himel HN, Liberati A, Gelber RD, Chalmers TC (1986)
Adjuvant chemotherapy for breast cancer: A pooled estimate based on results from published randomized control trials. JAMA 256:1148-1159.

View

Peto J, Eden OB, Lilleyman J, Richards S (1986)
Improvement in treatments for children with acute lymphoblastic leukaemia: The Medical Research Council UKALL Trials, 1972-84. Lancet 1:408-411.

View

Simes RJ (1986)
Publication bias: the case for an international registry of clinical trials. Journal of Clinical Oncology 4:1529-41.

View

Herxheimer A, Zentler-Munro P, Winn D (1986)
Therapeutic trials and society: making the best use of resources. London: Consumers Association.

View

Gøtzsche PC (1987)
Reference bias in reports of drug trials. BMJ 295:654-656.

View

Machin D, Campbell MJ (1987)
Statistical Tables for the Design of Clinical Trials. Oxford: Blackwell scientific publications.

View

Antiplatelet Trialists' Collaboration (1988)
Secondary prevention of vascular disease by prolonged anti-platelet treatment. BMJ 296:320-331.

View

Chalmers I, ed (1988)
The Oxford Database of Perinatal Trials. Oxford: Oxford University Press.

View

Early Breast Cancer Trialists' Collaborative Group (1988)
Effects of adjuvant tamoxifen and of cytotoxic therapy on mortality in early breast cancer. An overview of 61 randomized trials among 28,896 women. New England Journal of Medicine 319:1681-92.

View

Elbourne D, Prendiville W, Chalmers I (1988)
Choice of oxytocic preparation for routine use in the management of the third stage of labour: an overview of the evidence from controlled trials. British Journal of Obstetrics and Gynaecology 95:17-30.

View

Farr BM, Hendley JO, Kaiser DL, Gwaltney JM (1988)
Two randomized controlled trials of virucidal nasal tissues in the prevention of natural upper respiratory infections. Am J Epidemiol 128:1162-72.

View

ISIS-2 (second International Study of Infarct Survival) Collaborative Group (1988)
Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17 187 cases of suspected acute myocardial infarction: ISIS-2. Lancet 332:349–360.

View

King JF, Grant A, Keirse MJNC, Chalmers I (1988)
Betamimetics in preterm labour: an overview of the randomized controlled trials. British Journal of Obstetetrics and Gynaecology 95:211-222.

View

MacMahon S, Collins R, Peto R, Koster RW, Yusuf S (1988)
Effects of prophylactic lidocaine in suspected acute myocardial infarction. An overview of results from the randomized, controlled trials. JAMA 260:1910-6.

View

Prendiville W, Elbourne E, Chalmers I (1988)
The effects of routine oxytocic administration in the management of the third stage of labour: an overview of the evidence from controlled trials. British Journal of Obstetrics and Gynaecology 95:3-16.

View

Chalmers I, Enkin M, Keirse MJNC (1989)
Effective care in pregnancy and childbirth. Oxford: Oxford University Press.

View

Gyorkos TW, Frappier-Davignon L, MacLean JD, Viens P (1989)
Effect of screening and treatment on imported intestinal parasite infections: results from a randomized, controlled trial. American Journal of Epidemiology 129:753-61.

View

Hine LK, Laird N, Hewitt P, Chalmers TC (1989)
Meta-analytic evidence against prophylactic use of lidocaine in acute myocardial infarction. Archives of Internal Medicine 149:2694-8.

View

Gøtzsche PC (1989)
Methodology and overt and hidden bias in reports of 196 double-blind trials of nonsteroidal antiinflammatory drugs in rheumatoid arthritis. Control Clinical Trials 10:31-56.

View

Early Breast Cancer Trialists' Collaborative Group (1990)
Treatment of early breast cancer. Vol 1. Worldwide evidence, 1985-1990. Oxford: Oxford University Press.

View

Crowley P, Chalmers I, Keirse MJNC (1990)
The effects of corticosteroid administration before preterm delivery: an overview of the evidence from controlled trials. British Journal of Obstetrics & Gynaecology. 97:11–25.

View

Bartlett AV, Englender SJ, Jarvis BA, Ludwig L, Carlson JF, Topping JP (1991)
Controlled trial of Giardia lamblia: Control strategies in day care centers. American Journal of Public Health 81:1001-1006.

View

Advanced Ovarian Cancer Trialists Group (1991)
Chemotherapy in advanced ovarian cancer: an overview of randomised clinical trials. BMJ 303:884-893.

View

Antman EM, Lau J, Kupelnick B, Mosteller F, Chalmers TC (1992)
A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. JAMA 268:240-248.

View

Sinclair JC, Bracken MB (1992)
Effective care of the newborn infant. Oxford: Oxford University Press.

View

Cowley AJ, Skene A, Stainer, Hampton JR (1993)
The effect of lorcainide on arrhythmias and survival in patients with acute myocardial infarction. International Journal of Cardiology 40:161-166.

View

Cochrane Pregnancy and Childbirth Group (1994)
The Cochrane Pregnancy and Childbirth Database. Oxford: Update Software

View

Cholesterol Treatment Trialists’ (CTT) Collaboration (1995)
Protocol for a prospective collaborative overview of all current and planned randomized trials of cholesterol treatment regimens. American Journal of Cardiology 75:1130-1134.

View

Higgins JPT, Whitehead A (1996)
Borrowing strength from external trials in a meta-analysis. Statistics in Medicine 15:2733-2749.

View

Waller LA (1997)
A note on Harold S Diehl, randomization, and clinical trials. Controlled Clinical Trials 18: 180-183.

View

Zucker DR, Schmid CH, McIntosh MW, D'Agostino RB, Selker HP, Lau J (1997)
Combining single patient (N-of-1) trials to estimate population treatment effects and to evaluate individual patient responses to treatment. Journal of Clinical Epidemiology 50:410-410.

View

Murray DM (1998)
Design and Analysis of Group Randomized Trials. New York: Oxford University Press Inc.

View

Mahon JL, Laupacis A, Hodder RV, McKim DA, Paterson NA, Wood TE, Donner A (1999)
Theophylline for irreversible chronic airflow limitation: a randomized study comparing n of 1 trials to standard practice. Chest 115:38-48. PMID: 9925061

View

Djulbegovic B, Lacevic M, Cantor A, Fields KK, Bennett CL, Adams JR, Kuderer NM, Lyman GH (2000)
The uncertainty principle and industry-sponsored research. Lancet 356:635-638.

View

Yusuf S (2000)
Challenges in the conduct and interpretation of phase II (pilot) randomized trials. . American Heart Journal 139:S136-42.

View

Sutton AJ, Abrams KR, Jones DR, Sheldon T, Song F (2000)
Methods for Meta-Analysis in Medical Research. Chichester: Wiley.

View

Stangl D, Berry DA (2000)
Meta-Analysis in Medicine and Health Policy. New York: Marcel Dekker, Inc.

View

Horn J (2001)
Calcium antagonists in Stroke. ISBN 90-9014236-3.

View

Wagner AK, Soumerai SB, Zhang F, Ross-Degnan D (2002)
Segmented regression analysis of interrupted time series studies in medication use research. Journal of Clinical Pharmacy and Therapeutics 27:299–309.

View

Sandercock P, Roberts I (2002)
Systematic reviews of animal experiments. Lancet 360:586. DOI:https://doi.org/10.1016/S0140-6736(02)09812-4.

View

Melander H, Ahlqvist-Rastad J, Meijer G, Beermann B (2003)
Evidence b(i)ased medicine - selective reporting from studies sponsored by pharmaceutical industry: review of studies in new drug applications. BMJ 326:1171-3.

View

Wager E, Field EA, Grossman L (2003)
Good Publication Practice for pharmaceutical companies. Current Medical Research and Opinion 19:149-54.

View

Psaty BN, Lumley T, Furberg CD, Schellenbaum G, Pahor M, Alderman MH, Weiss NS (2003)
Health outcomes associated with various antihypertensive therapies used as first-line agents - a network meta-analysis. JAMA 289:2534-2544

View

Jones B, Kenward MG (2003)
Design and Analysis of Cross-Over-Trials (2nd Ed). London and USA: Chapman and Hall.

View

Whittington CJ, Kendall T, Fonagy P, Cottrell D, Cotgrove A, Boddington E (2004)
Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data. Lancet; 363:1341-1345.

View

O'Collins VE, Macleod MR, Donnan GA, Horky LL, van der Worp BH, Howells DW (2006)
1,026 experimental treatments in acute stroke. Annals of Neurology 59:467-77. https://doi.org/10.1002/ana.20741

View

Perel P, Roberts I, Sena E, Wheble P, Briscoe C, Sandercock S, Macleod M,  Mignini LE, Jayaram P, Khan KS (2007)
Comparison of treatment effects between animal experiments and clinical trials: systematic review. BMJ 334:197-200.

View

Glasziou P, Chalmers I, Rawlins M, McCulloch P (2007)
When are randomised trials unnecessary? Picking signal from noise. BMJ 334: 349-351.

View

Psaty BM, Kronmal RA (2008)
Reporting mortality findings in trials of Rofecoxib for Alzheimer disease or cognitive impairment. JAMA 299:1813-1817.

View

Djulbegovic B, Kumar A, Soares HP, Hozo I, Bepler G, Clarke M, Bennett CL (2008)
Treatment success in cancer: new cancer treatment successes identified in phase 3 randomized controlled trials conducted by the national cancer institute-sponsored cooperative oncology groups, 1955 to 2006. Archives of Internal Medicine. 168:632-42.

View

Rising K, Bacchetti P, Bero L (2008)
Reporting bias in drug trials submitted to the Food and Drug Administration: review of publication and presentation. PLoS Med 5(11): e217. doi:10.1371/journal.pmed.0050217

View

Trotta F, Apolone G, Garattini S, Tafuri G (2008)
Stopping a trial early in oncology: for patients or for industry? Annals of Oncology Feb 29; doi:10.1093/annonc/mdn042.

View

Turner EH, Matthews AM, Linardatos E, Tell RA, Rosenthal R (2008)
Selective publication of antidepressant trials and its influence on apparent efficacy. New England Journal of Medicine 358:252-60.

View

Sena ES, van der Worp HB, Bath PMW, Howells DW, Macleod MR (2010)
Publication bias in reports of animal Stroke studies leads to major overstatement of efficacy. PLoS Biol 8(3): e1000344. doi:10.1371/journal.pbio.1000344

View

Sena ES, Briscoe CL, Howells DW, Donnan GA, Sandercock PA, Macleod MR (2010)
Factors affecting the apparent efficacy and safety of tissue plasminogen activator in thrombotic occlusion models of stroke: systematic review and meta-analysis. Journal of Cerebral Blood Flow and Metabolism 30:1905-13.

View

Prinz F, Schlange T, Asadullah K (2011)
Believe it or not: how much can we rely on published data on potential drug targets? Nat Rev Drug Discov 10:712.

View

Turner EH, Knoepflmacher D, Shapley L (2012)
Publication bias in antipsychotic trials: an analysis of efficacy comparing the published literature to the US Food and Drug Administration database. PLoS Med 9(3):e1001189.

View

Goldacre B (2012)
Bad Pharma: how drug companies mislead doctors and harm patients. London: Fourth Estate.

View

Sena ES, Currie GL, McCann SK, Macleod MR, Howells DW (2014)
Systematic reviews and meta-analysis of preclinical studies: why perform them and how to appraise them critically. J Cereb Blood Flow Metab 34:737-742. doi:10.1038/jcbfm.2014.28

View

Jefferson T, Jones MA, Doshi P, Del Mar CB, Hama R, Thompson MJ, Spencer EA, Onakpoya I, Mahtani KR, Nunan D, Howick J, Heneghan CJ (2014)
Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children. Cochrane Database of Systematic Reviews 2014, Issue 4. Art. No.: CD008965. DOI:10.1002/14651858.CD008965.pub4.

View

Punja S, Xu D, Schmid CH, Hartling L, Urichuk L, Nikles CJ, Vohra S (2016)
N of 1 trials can be aggregated to generate group mean treatment effects: A systematic review and meta-analysis. Journal of Clinical Epidemiology 76:65-75.

View

de Vries YA, Roest AM, de Jonge P, Cuijpers P, Munafò MR, Bastiaansen JA (2018)
The cumulative effect of reporting and citation biases on the apparent efficacy of treatments: the case of depression. Psychological Medicine 48:2453-2455.

View

Pan H, Peto R, Karim QA, Alejandria M, Henao-Restrepo AM, García CH, Kieny MP, Malekzadeh R, Murthy S, Preziosi MP, Reddy S, Periago MR, Sathiyamoorthy V, Røttingen JA, Swaminathan S, WHO Solidarity trial consortium (2020)
Repurposed antiviral drugs for COVID-19 –interim WHO SOLIDARITY trial results. MedRxiv. doi: https://doi.org/10.1101/2020.10.15.20209817

View

RECOVERY Trial Team (2020)
Randomized Evaluation of COVID019 Therapy (RECOVERY). RECOVERY Central Coordinating Office, Oxford. www.recoverytrial.net

View

Horby P, Mafham M, Linsell L, Bell JL, Staplin N, Emberson JR, Wiselka M, Ustianowski A, Elmahi E, Prudon B, Whitehouse A, Felton T, Williams J, Faccenda J, Underwood J, Baillie JK, Chappell L, Faust SN, Jaki T, Jeffery K, Lim WS, Montgomery A, Rowan K, Tarning J, Watson JA, White NJ, Juszczak E, Haynes R, Landray MJ (2020)
Effect of Hydroxychloroquine in Hospitalized Patients with COVID-19: Preliminary results from a multi-centre, randomized, controlled trial. doi: https://doi.org/10.1101/2020.07.15.20151852

View

Horby P, Lim WS, Emberson J, Mafham M, Bell J, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffrey K, Montgomery A, Rowan K, Juszcak E, Baillie JK, Haynes R, Landray MJ, on behalf of the RECOVERY Collaborative Group (2020)
Effect of Dexamethasone in Hospitalized Patients with COVID-19: Preliminary Report. medRχiv. Doi: https://doi.org/10.1101/2020.06.22.20137273

View

Hahn RA, Teutsch SM (2021)
Saving lives by modifying the process of science: Estimated historical mortality associated with the failure to conduct routine prospective cumulative systematic reviews. American Journal of Biomed Science and Research 14(6):531-534.

View

D'Aquila RT, Hughes MD, Johnson VA, Fischl MA, Sommadossi JP, Liou SH, Timpone J, Myers M, Basgoz N, Niu M, Hirsch MS (2021)
Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV-1 infection. A randomized, double- blind, placebo-controlled trial. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators. Annals of Internal Medicine 124:1019-1030.

View

Show


Yoshioka AY (1998).
Streptomycin, 1946: British central administration of supplies of a new drug of American origin with special reference to clinical trials in tuberculosis. Philosophy Thesis, University of London. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Loudon I (2002).
The use of historical controls and concurrent controls to assess the effects of sulphonamides, 1936-1945. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Scadding JG (2002).
Reflections on my studies of the effects of sulphonamide drugs in bacillary dysentery in Egypt, 1943-1944. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Doll R (2003).
Controlled trials testing two or more treatments simultaneously. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Gong Y, Gluud C (2003).
Commentary on the Ben Cao Tu Jing (11th century). Atlas of Materia Medica. Song Dynasty (960-1279). JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Rolls R (2003).
Caleb Hillier Parry (1755-1822). JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Silverman WA† (2003).
Personal reflections on lessons learned from randomized trials involving newborn infants, 1951 to 1967. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Tröhler U (2003).
Withering’s 1785 appeal for caution when reporting on a new medicine. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Vandenbroucke JP (2003).
Thalidomide: an unanticipated adverse effect. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Vandenbroucke JP (2003).
Aspirin: an unanticipated beneficial effect. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Armitage P† (2003).
Some recollections of the early years of the Medical Research Council (MRC) Statistical Research Unit. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Bastian H (2004).
Down and almost out in Scotland: George Orwell, tuberculosis and getting streptomycin in 1948. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Clarke M (2004).
The 1944 patulin trial of the British Medical Research Council: an example of how concerted common purpose can get reliable answers to important questions very quickly. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Diaz M, Neuhauser D (2004).
Lessons from using randomization to assess gold treatment for tuberculosis. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Elwood P (2004).
The first randomized trial of aspirin for heart attack and the advent of systematic overviews of trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Hampton J (2004).
An early parallel group trial in cardiology. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Houston C (2004).
Ferguson’s BCG research – Canada’s first randomized clinical trial? JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Lee MR (2004).
The miracle of St. Alfege’s: discovering a treatment for myaesthenia gravis. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Crofton J† (2005).
Marc Daniels (1907-1953), a pioneer in establishing standards for clinical trial methods and reporting. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Hemminki E (2005).
Commentary on an early placebo controlled trial in Finland. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Lee MR (2005).
William Withering (1741-1799), a biographical sketch of a Birmingham Lunatic. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Volmink J (2005).
The willow as a Hottentot (Khoikhoi) remedy for rheumatic fever. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Boren SA, Diaz M, Neuhauser D (2006).
James Burns Amberson (1890-1979). JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Craft A (2006).
James Stansfeld (1917-1998). JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Crofton J† (2006).
John Crofton (1912-2009). JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Neuhauser D, Diaz M (2006).
Jesse GM Bullowa (1879-1943). JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Tansey EM (2006).
Philip Montagu D’Arcy Hart (1900-2006). JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Louis-Courvoisier M (2007).
An 18th century controlled trial prompted by a potential shortage of hospital beds. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Nasser M, Tibi A, Savage-Smith E (2007).
Ibn Sina’s Canon of Medicine: 11th century rules for assessing the effects of drugs. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Adams CE (2009).
James Crichton Browne and controlled evaluation of drug treatment for mental illness. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Armitage P† (2009).
A statistical note on the analysis of the 1948 MRC streptomycin trial. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Chalmers I, Toth B (2009).
19th century controlled trials to test whether belladonna prevents scarlet fever. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Furberg CD (2009).
How should one analyse and interpret clinical trials in which patients don’t take the treatments assigned to them? JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Moore W (2009).
John Hunter: learning from natural experiments, ‘placebos’, and the state of mind of a patient in the 18th century. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Moore W (2009).
John Hunter (1728-1793). JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Williams KJ (2009).
The introduction of ‘chemotherapy’ using arsphenamine – the first magic bullet. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Chalmers I (2010).
Why the 1948 MRC trial of streptomycin used treatment allocation based on random numbers. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Cook H (2010).
Testing the effects of Jesuit’s bark in the Chinese Emperor’s court. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Klingberg MA (2010).
An epidemiologist’s journey from typhus to thalidomide, and from the Soviet Union to Seveso. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Spain P, Kadan-Lottick N (2010).
Observations of unprecedented remissions following novel treatment for acute leukemia in children in 1948. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Doyle D (2011).
Thomas John MacLagan (1838-1903). JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Doyle D (2011).
Thomas MacLagan’s 1876 demonstration of the dramatic effects of salicin in rheumatic fever. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Fox DM (2011).
Systematic reviews and health policy: the influence of a project on perinatal care since 1988. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Gartlehner G, Stepper K (2011).
Julius Wagner-Jauregg: pyrotherapy, Simultanmethode, and ‘racial hygiene’. JLL Bulletin: Commentaries on the history of treatment evaluation.

View

Maehle A-H (2011).
Four early clinical studies to assess the effects of Peruvian bark. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Marušić A, Fatović-Ferenčić S (2012).
Adoption of the double dummy trial design to reduce observer bias in testing treatments. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Milne I (2012).
Who was James Lind, and what exactly did he achieve? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Gachelin G (2013).
The interaction of scientific evidence and politics in debates about preventing malaria in 1925. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Bryder L (2014).
The Medical Research Council and treatments for tuberculosis before streptomycin. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Dean ME (2014).
The mustard gas experiments done by the British Homoeopathic Society for the Ministry of Home Security, 1941-42. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2014).
Statistics and the British controversy about the effects of Joseph Lister’s system of antisepsis for surgery, 1867-1890. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Hampton J (2015).
Therapeutic fashion and publication bias: the case of anti-arrhythmic drugs in heart attack. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Sackett DL† (2015).
Why did I become a clinician-trialist? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Toth B (2015).
Why the MRC Therapeutic Trials Committee didn’t introduce controlled clinical trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Schlesselman JJ (2015).
Jerome Cornfield’s Bayesian approach to assessing interim results in clinical trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Gachelin G, Garner P, Ferroni E, Tröhler U, Chalmers I (2016).
Evaluating Cinchona bark and quinine for treating and preventing malaria. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Peto J (2016).
Reflections on the importance of strict adherence to treatment protocols: acute lymphoblastic leukaemia in children in the 1970s in the US and the UK. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Peto R (2016).
Reflections on the design and analysis of clinical trials and meta-analyses in the 1970s and 1980s. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Zwarenstein M (2016).
‘Pragmatic’ and ‘Explanatory’ attitudes to randomized trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Altman DG† (2017).
Donald Mainland: anatomist, educator, thinker, medical statistician, trialist, rheumatologist. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Altman DG† (2017).
Avoiding bias in trials in which allocation ratio is varied. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Pollock JI (2017).
A controlled trial using a factorial design reported in 1946. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Senn SJ (2017).
Cushny and Peebles, optical isomers, and the birth of modern statistics. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Toth B (2018).
Pioneering controlled trials of treatments for erysipelas and pneumonia in Glasgow, 1936-47. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Garattini S (2018).
Italian controlled trials to assess prevention and treatment of malaria, 1900-1930s. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tognoni G, Franzosi MG, Garattini S (2018).
Embedding patient- and public health-oriented research in a national health service: the GISSI experience. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Marson Smith P, Colquhoun D, Chalmers I (2019).
John Henry Gaddum’s 1940 guidance on controlled clinical trials JLL Bulletin: Commentaries on the history of treatment evaluation.

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Meinert C† (2019).
The trials and tribulations of the University Group Diabetes Program: lessons and reflections. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Jefferson T (2019).
Sponsorship bias in clinical trials – growing menace or dawning realisation? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Tröhler U (2020)
Probabilistic thinking and the evaluation of therapies, 1700-1900. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Glasziou PP, Tikkinen KAO (2021).
The RECOVERY trial platform: a milestone in the development and execution of treatment evaluation during an epidemic. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Gøtzsche PC (2021).
Citation bias: questionable research practice or scientific misconduct? JLL Bulletin: Commentaries on the history of treatment evaluation.

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Senn SJ, Chalmers I (2021).
Giving and taking: ethical treatment assignment in controlled trials. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Podolsky SH (2022).
The (Harry) Gold Standard: angina, suggestion, and the path to the “double-blind” test and Clinical Pharmacology. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Ritskes-Hoitinga M, Pound P (2022).
The role of systematic reviews in identifying the limitations of preclinical animal research, 2000 – 2022. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Chalmers I, Matthews R, Glasziou P, Boutron I, Armitage P† (2023).
Analysis of clinical trial by Treatment Allocated or by Treatment Received? Applying ‘the intention-to-treat principle’. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Nylenna, M (2023).
Paul Owren, Christopher Bjerkelund and the dawn of controlled trials in Norway. JLL Bulletin: Commentaries on the history of treatment evaluation.

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Glasziou P, Matthews R, Boutron I, Chalmers I, Armitage P† (2023)
The differences and overlaps between ‘explanatory’ and ‘pragmatic’ controlled trials: a historical perspective. JLL Bulletin: Commentaries on the history of treatment evaluation.

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