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Context
Principles of testing
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Daniel (6th century BCE)
The Book of Daniel, Chapter 1:1-16.
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al-Razi (10th century CE; 4th Century AH)
Kitab al-Hawi fi al-tibb.
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Ibn Hindu (10th-11th century CE; 4th-5th century AH)
Miftah al-tibb wa-minhaj al-tullab [The key to the science of medicine and the students' guide].
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Ben Cao Tu Jing (11th century)
Atlas of Materia Medica.
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Ibn Sina (c. 1012 CE; c. 402 AH)
Kitab al-Qanun fi al-tibb [Avicenna’s The Canon of Medicine].
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Abd al-Latif ibn Yusuf al-Baghdadi (13th century CE, 7th century AH)
The Book of the Two Pieces of Advice by Abd al-Latif, the son of Yusuf, to the General Public (Kitab al-Nasihatain min Abd al-Latif b. Yusuf ila l-nas kaffatan).
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Petrarca F (1364)
Rerum Senilium Libri. Liber XIV, Epistola 1. Letter to Boccaccio (V.3). [Letters of old age.].
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Fioravanti L (1573)
Communication addressed to "Illustrissimo e Eccellentissimo Signor Al Protofisico Boldon e al Vicario di Giustizia", 22 xxxx 1573.
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Bacon F (1645)
Franc Baconis de Verulamio / Summi Angliae Cancellarii /Novum organum scientiarum.
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Nettleton T (1722)
Part of a letter from Dr. Nettleton, physician at Halifax, to Dr. Jurin, R. S. Sec concerning the inoculation of the small pox, and the mortality of that distemper in the natural way.
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Massey I (1723)
A short and plain account of inoculation. With some remarks on the main argument made use of to recommend that practice, by Mr. Maitland and others. To which is added, a letter to the learned James Jurin, M.D.R.S. Secr. Col. Reg. Med. Lond. Soc.
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Clifton F (1732)
The state of physick, ancient and modern, briefly considered: with a plan for the improvement of it.
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Hillary W (1761)
An inquiry into the means of improving medical knowledge.
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Lind J (1762)
An essay on the most effectual means of preserving the health of seamen, in the Royal Navy.
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Lind J (1763)
Two papers on fevers and infection.
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Watson W (1768)
An account of a series of experiments, instituted with a view of ascertaining the most successful method of inoculating the smallpox.
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Lind J (1771)
An essay on diseases incidental to Europeans in hot climates.
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Aikin J (1771)
Thoughts on hospitals.
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Gregory J (1772)
Lectures on the duties and qualifications of a physician.
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Sims J (1774)
A discourse on the best methods of prosecuting medical enquiries.
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Lettsom JC (1775)
On the improvement of medicine in London on the basis of public good
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Millar J (1777)
Observations on the practice in the medical department of the Westminster General Dispensary.
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Dobson M (1779)
A medical commentary on fixed air.
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Millar J (1779)
Observations on the management of the prevailing diseases particularly in the Army and Navy.
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Clark J (1780)
Observations on fevers, especially of the continued type.
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Home F (1780)
Clinical experiments, histories and dissections.
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Black W (1782)
An historical sketch of medicine and surgery from their origin to the present time.
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Commission Royale. Bailly A (1784)
Rapport des commissaires chargés par le Roi, de l'examen du magnétisme animale. Imprimé par ordre du Roi.
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Lavoisier A-L de (c 1784)
Undated documents contained in: Mémoires de Lavoisier, Oeuvres, Tome III.
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Fowler T (1785)
Medical reports of the effects of tobacco in the cure of dropsies and dysuries....
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Fowler T (1786)
Medical reports of the effects of arsenic in the cure of agues, remitting feveres and periodic headachs.
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Black W (1788)
A comparative view of the mortality of the human species at all ages.
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Percival T (1788)
Essays medical, philosophical and experimental
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Black W (1789)
An arithmetical and medical analysis of the diseases and mortality of the human species.
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Robertson R (1789)
Observations on jail, hospital, or ship fever.
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Robertson R (1790)
Essay on fever.
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Clark J (1792)
Observations on the diseases which prevail in long voyages to hot countries.
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Ferriar J (1792)
Medical histories and reflections. Vol 1.
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Fordyce G (1793)
An attempt to improve the evidence of medicine.
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Rowley W (1793)
The causes of a great number of deaths amongst adults and children. 2nd edn.
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Hunter J (1794)
A treatise on the blood, inflammation and gun-shot wounds.
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Ferriar J (1795)
Medical histories and reflections. Vol. 2.
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Fordyce G (1798)
A third dissertation on fever, Parts I & II.
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Fordyce G (1803)
A fifth dissertation on fever.
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Currie W (1804)
Medical reports of the effects of water: cold and warm as a remedy in fever and febrile diseases.
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Blane G (1813)
Observations on the comparative prevalence, mortality, & treatment of different diseases....
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Guthrie GJ (1815)
A treatise on gun-shot wounds.
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Hutchinson AC (1817)
Some further observations on the subject of the proper period for amputating in gun-shot wounds.
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Marcet A (1819)
An essay on the chemical history and medical treatment of calculous disorders.
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Prout WM (1821)
An inquiry into the nature and treatment of gravel, calculus and other diseases connected with a deranged operation of the urinary organs.
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Richerand A (1825)
Histoire des progrès récens de la chirurgie.
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Hawkins FB (1829)
The elements of medical statistics.
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Yelloly J (1829)
Remarks on the tendency to calculous diseases with observations on the nature of urinary concretions.
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Todd TJ (1831)
The book of analysis or a new method of experience....
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Bostock J (1833)
History of medicine.
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Louis PCA (1835)
Recherches sur les effets de la saignée dans quelques maladies inflammatoires et sur l'action de l'émétique et des vésicatoires dans la pneumonie.
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Bigelow J (1835)
A discourse on self-limited diseases, delivered before the Massachusetts Medical Society at their annual meeting, May 27, 1835.
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Gavarret LDJ (1840)
Principes généraux de statistique médicale: ou développement des régles qui doivent présider à son emploi.
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Alcock R (1840)
Observations on injuries of joints and their treatment.
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Bartlett E (1844)
An essay on the philosophy of medical science.
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Forbes J (1846)
Homoeopathy, allopathy and “young physic”.
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Balfour TG (1854)
Quoted in West C. Lectures on the Diseases of Infancy and Childhood.
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Holmes OW (1861)
Currents and countercurrents in medical science with other addresses and essays.
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Mill JS (1862)
A system of logic ratiocinative and inductive. 5th Edn,vol 1.
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Béclard PA (1863)
Rapport général sur les prix décernés en 1862.
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Barclay AW (1864)
Medical errors: fallacies connected with the application of the inductive method of reasoning to the science of medicine.
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Bernard C (1865)
Introduction à l'étude de la médicine expérimentale.
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Sutton HG (1865)
Cases of rheumatic fever treated for the most part by mint water.
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Bain A (1870)
Logic.
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Wanscher O (1877)
Om Diphteritis og Croup - særligt med hensyn til Tracheostomien ved samme. [On diphtheria and croup - especially regarding tracheostomy in this condition].
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Ephraim A (1890-1894)
Uber die Bedeutung de statistischen Methode für die Medicin.
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Andrew J (1891)
Harveian Oration.
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Behring EA, Boer, Kossel H (1893)
Zur Behandlung diphtheriekranker Menschen mit Diphtherieheilserum.
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Haffkine WM (1896)
Correspondence: Explanation of his inoculation report forms.
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Heiberg P (1897)
Studier over den statistiske undersøgelsesmetode som hjælpemiddel ved terapeutiske undersøgelser [Studies on the statistical study design as an aid in therapeutic trials].
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Rivers WHR (1908)
The influence of alcohol and other drugs on fatigue.
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Freeman J (1910)
Vaccine therapy.
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Sollmann T (1917)
The crucial test of therapeutic evidence.
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Bleuler E (1919)
Das undisziplinierte Denken in der Medizin und seine Überwindung.
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Locke EA (1924)
The serologic treatment of lobar pneumonia.
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Lewis S (1925)
Arrowsmith.
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Bullowa JGM (1928b)
The control. Contribution to a symposium on the use of antipneumococcic refined serum in lobar pneumonia, 15 December 1927.
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Greenwood M (1934)
Epidemics and crowd-diseases.
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Medical Research Council Therapeutic Trials Committee (1934)
The serum treatment of lobar pneumonia.
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Medical Research Council Therapeutic Trials Committee. (1934)
$Duplicate The serum treatment of lobar pneumonia - Duplicate BMJ entry
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Sutliff WD (1936)
Adequate tests of curative therapy in man.
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Bentley PJ (1936)
Artificial pneumothorax: experience of the London County Council.
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Bentley PJ (1936)
Artificial pneumothorax: experience of the London County Council.
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Parrot A, Catanei A, Ambialet R, Clastrier J (1937)
Comparative experiments in mass prophylaxis of malaria by means of quinine and synthetic drugs (quinacrine and praequine).
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Editorial (1937)
Mathematics and medicine.
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Bullowa JGM (1937)
Serum therapy. In: Bullowa JGM. The management of the pneumonias.
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Hill AB (1937a)
Principles of medical statistics. I. The aim of the statistical method; and General summary and conclusions.
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Hill AB (1937b)
Principles of medical statistics.
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Hill AB (1937c)
Artificial pneumothorax on statistical trial.
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Mainland D (1938)
The treatment of clinical and laboratory data: an introduction to statistical ideas and methods for medical and dental workers.
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Gaddum JH (1940)
Pharmacology.
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Hinshaw HC, Feldman WH (1944)
Evaluation of therapeutic agents in clinical tuberculosis.
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Marshall EK (1949)
Clinical therapeutic trial of a new drug.
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Editorial (1950)
Are statistics necessary?
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Reid DD (1950)
Statistics in clinical research.
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Daniels M (1951)
Clinical evaluation of chemotherapy in tuberculosis.
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Hill AB (1951)
The clinical trial.
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Hill AB (1952)
The clinical trial.
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Hogben L (1954)
The assessment of remedies.
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Lasagna L (1955)
The controlled clinical trial: theory and practice.
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Cox DR (1958)
Planning of experiments.
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Atkinson (1958)
Testing
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Doll R (1959)
Practical problems of drug trials in clinical practice.
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Oldham PD (1959)
Clinical and field trials.
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Zubrod CG, Schneiderman M, Frei E, Brindley C, Gold GL, Shnider B, Oviedo R, Gorman J, Jones R, Jonsson U, Colsky J, Chalmers T, Ferguson B, Dederick M, Holland J, Selawry O, Regelson W, Lasagna L, Owens AH (1960)
Appraisal of methods Appraisal of methods for the study of chemotherapy in man: Comparative therapeutic trial of nitrogen mustard and thiophosphoramide.
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Cochran WG (1961)
Designing clinicial trials. In: Forster FM, ed. Evaluation of drug therapy.
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Schneidermann MA (1966)
Therapeutic trials in cancer.
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Schwartz D, Lellouch J (1967)
Explanatory and pragmatic attitudes in therapeutic trials.
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Schwartz D, Flamant R, Lellouch J (1970)
L’essai thérapeutique chez l‘homme.
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Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, Mantel N, McPherson K, Peto J, Smith PG (1976)
Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design.
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Bunker JP, Barnes BA, Mosteller F (1977)
Costs, risks and benefits of surgery.
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Pocock SJ (1977)
Randomised clinical trials.
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Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, Mantel N, McPherson K, Peto J, Smith PG (1977)
Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples.
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Farquhar JW (1978)
The community-based model of life style intervention trials.
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Sackett DL (1979)
Bias in analytic research.
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Pocock SJ (1983)
Clinical trials: a practical approach.
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Bulpitt CJ (1984)
Randomised controlled clinical trials.
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Peto J, Eden OB, Lilleyman J, Richards S (1986)
Improvement in treatments for children with acute lymphoblastic leukaemia: The Medical Research Council UKALL Trials, 1972-84.
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Jenicek M (1987)
Méta-analyse en médecine. Évaluation et synthèse de l’information clinique et épidémiologique.
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Jenicek M (1989)
Meta-analysis in medicine: where we are and where we want to go.
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Pocock SJ, Hughes MD (1989)
Practical problems in interim analyses, with particular regard to estimation.
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O’Rourke K, Detsky AS (1989)
Meta-analysis in medical research: strong encouragement for higher quality in individual research efforts.
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Perel P, Roberts I, Sena E, Wheble P, Briscoe C, Sandercock S, Macleod M, Mignini LE, Jayaram P, Khan KS (2007)
Comparison of treatment effects between animal experiments and clinical trials: systematic review.
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Djulbegovic B, Kumar A, Soares HP, Hozo I, Bepler G, Clarke M, Bennett CL (2008)
Treatment success in cancer: new cancer treatment successes identified in phase 3 randomized controlled trials conducted by the national cancer institute-sponsored cooperative oncology groups, 1955 to 2006.
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